PMID:
Heliyon. 2019 May ;5(5):e01739. Epub 2019 May 17. PMID: 31193394
Abstract Title:
Antihyperlipidemic screening and plasma uric acid reducing potential ofseeds on Swiss albino mice model.
Abstract:
The global prevalence of hyperlipidaemia is increasing rapidly and high dietary fat intake is a major risk factor for developing hyperlipidaemia. Anbiological investigation was carried out on ethanolic extract ofa plant belonging to the family Cucurbitaceae for the evaluation of antihyperlipidemic activity and serum uric acid reducing potential. In our study, 25 healthy male mice were selected randomly and grouped into 5 groups (5 animals in each group). Lipid and uric acid profile were estimated after 21 days of treatment by using the enzymatic colourimetric GPO-PAP method. Results showed that ethanolic extract ofat a dose of 200 mg/kg body weight showed significant (p
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