PMID:
J Food Biochem. 2019 Jul ;43(7):e12885. Epub 2019 May 7. PMID: 31353690
Abstract Title:
Erectile dysfunction attenuation by naringenin in streptozotocin-induced diabetic rats.
Abstract:
Diabetes mellitus is associated with sexual dysfunction, which leads to infertility in animal models. The aim of this study was to evaluate sexual behavior in diabetic rats administered with naringenin. Rats were classified into five groups including healthy controls, those with STZ-induced diabetes, and those with STZ-induced diabetes then treated with 25, 50, or 100 mg kg dayof naringenin. Male rats were introduced to sexually receptive females, and data were collected regarding sexual behavior and erectile activity. Blood samples were taken and histopathological analyses were carried out. ANOVA and the Student-Newman-Keuls t test were used for statistical comparisons. Sexual behavioral, mount latency, intromission latency, ejaculation latency, and postejaculatory interval were significantly increased in diabetic rates compared with controls (p