PMID:
Biochim Open. 2016 Dec ;3:19-25. Epub 2016 Jul 25. PMID: 29450127
Abstract Title:
Mobile phones electromagnetic radiation and NAD-dependent isocitrate dehydrogenase as a mitochondrial marker in asthenozoospermia.
Abstract:
NAD-dependent Isocitrate Dehydrogenase (NAD-IDH) could be one of the cell phone radiation targets. Enzyme activity alteration may lead to decline in sperm motility during radio-frequency electromagnetic waves (RF-EMW) exposure. The current case control study aimed to investigate the possible relationship between mitochondrial NAD-IDH activity in human seminal plasma and sperm motility among asthenozoospermic cellular phone users. A total number of ninety idiopathic infertile males referred from the Department of Dermatology and Andrology, were enrolled in this study. NAD-IDH activity was measured in human seminal plasma by spectrophotometer. Computer-aided sperm analysis (CASA) following WHO criteria has been used for semen analyses. The results showed that IDH activity was increased in patients with prolonged cell phone daily use≥4 h/day. Its level, correlated negatively with either the motility ratio percentages (r = -0.46,
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