PMID:
Clin Respir J. 2019 Jul 16. Epub 2019 Jul 16. PMID: 31310707
Abstract Title:
Effect of moderate exercise under hypoxia on Th1/Th2 cytokine balance.
Abstract:
INTRODUCTION AND OBJECTIVE: Moderate exercise performed in normoxia can be immunostimulatory, while strenuous exercise can be immunosuppressive. However, less is known about the effects of exercise under hypoxia on cytokines. The aim of this study was to evaluate the effects of an acute exercise session performed under hypoxia similar to an altitude of 4200 m on cytokine balance. Our hypothesis was that exercise, even of moderate intensity, associated with hypoxia may induce different changes in relation to the normoxic condition.METHODS: Eight healthy male volunteers were exercised on a treadmill for 1 hour at an intensity of 50% VOunder normoxic or hypoxic condition (4200 m). Blood samples were collected at rest and immediately 1 hour after the exercise, respectively to determine cytokines, hormones and metabolites. The two-way ANOVA and the Bonferroni post hoc test were used and the significance adopted was P
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