PMID:
J Microbiol Biotechnol. 2018 Aug 28 ;28(8):1247-1259. PMID: 29943551
Abstract Title:
Dietary Supplementation with Raspberry Extracts Modifies the Fecal Microbiota in Obese Diabetic db/db Mice.
Abstract:
Raspberries are polyphenol-rich fruits with the potential to reduce the severity of the clinical signs associated with obesity, a phenomenon that may be related to changes in the gut microbiota. The aim of this study was to investigate the effect of raspberry supplementation on the fecal microbiota using an in vivo model of obesity. Obese diabetic db/db mice were used in this study and assigned to two experimental groups (with and without raspberry supplementation). Fecal samples were collected at the end of the supplementation period (8 weeks) and used for bacterial 16S rRNA gene profiling using a MiSeq instrument (Illumina). QIIME 1.8 was used to analyze the 16S data. Raspberry supplementation was associated with an increased abundance of Lachnospiraceae (= 0.009), a very important group for gut health, and decreased abundances of, and the fiber degrader S24-7 family as well as unknown groups of Bacteroidales and Enterobacteriaceae (
Health Time 