PMID:
Int J Clin Pract. 2018 Jun ;72(6):e13211. Epub 2018 May 31. PMID: 29855123
Abstract Title:
Low serum zinc level: The relationship with severe pneumonia and survival in critically ill children.
Abstract:
BACKGROUND: Zinc deficiency is common among children in developing countries; but, there is still conflicting evidence on whether the alteration in zinc metabolism is the predictive of disease severity in the setting of critical illness.OBJECTIVES: To assess serum zinc levels in children admitted with pneumonia, and also to study the relationship between zinc levels and severity and mortality from pneumonia.METHODS: In a prospective cohort study, we enrolled 320 critically ill children admitted to the paediatric intensive care unit (PICU) with severe pneumonia (group 1) in addition to 160 children admitted into wards with pneumonia (group 2). Serum zinc measured in all patients on admission.RESULTS: Serum zinc level was significantly lower among patients admitted to PICU (group 1) compared with patients admitted to wards (group 2) (P