PMID:
Nutr Cancer. 2019 Aug 7:1-14. Epub 2019 Aug 7. PMID: 31387393
Abstract Title:
Multi-Targeting by-Elemene and Its Anticancer Properties: A Good Choice for Oncotherapy and Radiochemotherapy Sensitization.
Abstract:
Several studies have focused on chemical agents, tailored from natural edible products, used to prevent and treat various diseases.β-elemene is a well-known compound derived fromthat possesses a wide spectrum of anticancer properties under preclinical and clinical conditions. Several studies have demonstrated its inhibitory effect both in humans and animals with cancers. Numerousandexperimental models have revealed thatβ-elemene can modulate multiple molecular pathways involved in carcinogenesis. In general, (1) β-elemene itself can inhibit and kill tumor cells through a variety of mechanisms, and (2) can synergistically enhance the effect of radiotherapy and/or chemotherapy, (3) also can regulate autoimmune inthe treatment of tumors. In this article, we critically focused on the available scientific evidence discussing the use of β-elemene in cancer prevention, and its molecular targets and mechanisms of action in different types of cancer. In addition, we have discussed its sources, chemistry, bioavailability, and future research directions.
Health Time 