PMID:
Curr Pharm Biotechnol. 2019 08 22. Epub 2019 Aug 22. PMID: 31438827
Abstract Title:
Coffea arabica bean extracts and vitamin C: A novel combination unleashes MCF-7 cell death.
Abstract:
BACKGROUND: Vitamin C (VC) is believed to enhance immunity and is regularly integrated as a supplementary agent during several treatments.OBJECTIVE: The green (GC) and roasted (RC) Coffee (Coffea arabica) aqueous extracts (0, 125, 250 and 500μg/ml) combined with VC (50 μg/ml) were examined on the cancerous MCF-7 cell line and normal human lymphocytes.METHODS: Neutral red uptake assay, comet assay, immunocytochemical reactivity for protein expression and mRNA expression of apoptosis-related genes were done.RESULTS: A significant (P
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