PMID:
Clin Nutr. 2019 Aug 27. Epub 2019 Aug 27. PMID: 31495735
Abstract Title:
Association between vitamin D status and sepsis in children: A meta-analysis of observational studies.
Abstract:
BACKGROUND: The consequences of vitamin D deficiency regarding sepsis in children remain controversial. We conducted a meta-analysis of studies evaluating the association between vitamin D status and sepsis in children.METHODS: We used EMBASE, Ovid Medline and Cochrane Library to conduct a meta-analysis of studies published in English before November 21, 2017.RESULTS: Among 1146 initially identified studies, we included 13 studies according to predefined inclusion criteria comprising 975 patients and 770 control participants. According to a random effects model, the mean difference in 25(OH)D levels (nmol/L) between participants with sepsis (444) and controls (528) was (mean difference, -18.55; 95% confidence interval (CI), -19.45 to -17.66, p
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