PMID:
Bratisl Lek Listy. 2015 ;116(2):96-100. PMID: 25665474
Abstract Title:
The effect of melatonin on the liver of rats exposed to microwave radiation.
Abstract:
OBJECTIVES: We aimed to clarify if melatonin treatment (2 mg/kg i.p.) may favorably impact the liver tissue in rats exposed to microwave radiation. The experiment was performed on 84 six-weeks-old Wistar male rats exposed for 4h a day, for 20, 40 and 60 days, respectively, to microwaves (900 MHz, 100-300 microT, 54-160 V/m). Rats were divided in to four groups: I (control) – rats treated with saline, II (Mel) – rats treated with melatonin, III (MWs) – microwave exposed rats, IV (MWs + Mel) – MWs exposed rats treated with melatonin. We evaluated oxidative stress parameters (malondialdehyde and carbonyl group content), catalase, xanthine oxidase, deoxyribonuclease I and II activity.BACKGROUND: Oxidative stress is the key mechanism of the microwave induced tissue injury. Melatonin, a lipophilic indoleamine primarily synthesized and released from the pineal gland is a powerful antioxidant.RESULTS: Exposure to microwaves caused an increase in malondialdehyde after 40 (p
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