PMID:
Cardiovasc Hematol Disord Drug Targets. 2019 Jun 12. Epub 2019 Jun 12. PMID: 31195951
Abstract Title:
Antihyperglycemic effect of the aqueous extract of Foeniculum vulgare in normal and streptozotocin-induced diabetic rats.
Abstract:
BACKGROUND: Diabetes mellitus is associated with high blood glucose levels due to insulin shortcoming (insulinopenia) or defective in insulin action. The objective of the study was to investigate the antidiabetic and antioxidant effects of Foeniculum vulgare in streptozotocin-induced diabetic rat.METHODS: The effects of the leaves aqueous extract (LAE) of Foeniculum vulgare (F. vulgare) at a dose of 10 mg/kg on blood glucose levels were evaluated in normal and streptozotocin (STZ)-induced diabetic rats. Histopathological changes were also evaluated in liver in STZ-induced rats.RESULTS: Single oral administration of F. vulgare LAE reduced blood glucose levels 6 h after administration in STZ diabetic rats (p
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