PMID:
Med Hypotheses. 2019 Oct ;131:109320. Epub 2019 Jul 20. PMID: 31443769
Abstract Title:
The sour side of vitamin C might mediate neuroprotective, anticonvulsive and antidepressant-like effects.
Abstract:
In animal experiments, neuroprotective, anticonvulsive and antidepressant-like properties have been increasingly attributed to administrations of ascorbic acid (AA, vitamin C) in at least medium (low millimolar) doses, which however await validation in well controlled clinical studies. In mammalian cortical and subcortical neurons, small to modest acidification (