PMID:
Int J Radiat Biol. 2013 Dec ;89(12):1053-60. Epub 2013 Jul 15. PMID: 23786626
Abstract Title:
Can safe and long-term exposure to extremely low frequency (50 Hz) magnetic fields affect apoptosis, reproduction, and oxidative stress?
Abstract:
PURPOSE: To determine whether 50 Hz extremely low frequency-magnetic fields (ELF-MF) affects apoptotic processes, oxidative damage, and reproductive characteristics such as sperm count and morphology in rat testes.MATERIALS AND METHODS: Thirty male Sprague-Dawley rats were used in the present study, which were divided into three groups (sham group, n = 10, and two experimental groups, n = 10 for each group). Rats in the experimental group were exposed to 100 and 500μT ELF-MF (2 h/day, 7 days/week, for 10 months) corresponding to exposure levels that are considered safe for humans. The same experimental procedures were applied to the sham group, but the ELF generator was turned off. Tissues from the testes were immunohistochemically stained for active (cleaved) caspase-3 in order to measure the apoptotic index by a semi-quantitative scoring system. The levels of catalase (CAT), malondialdehyde (MDA), myeloperoxidase (MPO), total antioxidative capacity (TAC), total oxidant status (TOS), and oxidative stress index (OSI) were also measured. Additionally, epididymal sperm count and sperm morphology was evaluated.RESULTS: There were no significant differences in the reproductive and oxidative stress parameters between the sham group and the exposed groups (p>0.05). While no difference was observed between the final apoptosis score of the sham and the 100μT ELF-MF group (p>0.05), the final apoptosis score was higher in the 500μT ELF-MF exposure group than in the sham group (p
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