Z. multiflora treatment improved learning and memory impairment as well as lung inflammation and oxidative stress induced by inhaled paraqut.

PMID: 

Nutr Neurosci. 2019 Oct 4:1-14. Epub 2019 Oct 4. PMID: 31583983

Abstract Title: 

The effect ofhydroalcoholic extract on memory and lung changes induced by rats that inhaled paraquat.

Abstract: 

The effects of hydroalcoholic extract of() on memory changes, as well as lung injury due to inhaled paraqut (PQ) in rat, were examined.Control group of rat with saline aerosol administration, PQ groups with PQ aerosol (27 and 54 mg/m) administration, PQ groups treated with two doses of the extract (200 and 800 mg/kg/day) and dexamethasone (0.03 mg/kg/day) were studied. Shuttle box and Morris Water Maze (MWM) tests were carried out as well as oxidant, anti-oxidant markers, total and differential white blood cell (WBC) counts and cytokine levels in broncho-alveolar lavage (BALF).Inhaled PQ significantly increased the escape latency and travelled distance in MWM test, but the time spent in the target quadrant on the probe day was significantly reduced (

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