PMID:
Pathophysiology. 2000 Jul ;7(2):127-130. PMID: 10927192
Abstract Title:
Pulsed magnetic fields enhance nitric oxide synthase activity in rat cerebellum.
Abstract:
The effect of pulsed magnetic fields on nitric oxide synthase (NOS) activity in the rat brain was investigated. Sprague-Dawley rats (male, 200-250 g body weight) brain were dissected regionally, and the crude enzyme solutions were treated with pulsed DC, AC or static DC magnetic fields at 0 degrees C for 1 h. After exposure, NOS activity was measured as nitrite and nitrate levels generated from incubation with arginine, CaCl(2) and beta-nicotinamide adenine dinucleotide phosphate. Under these experimental conditions, neither AC nor static DC field treatment showed any significant change in NOS activity. A significant increase in NOS activity was observed in the cerebellum (111.2+/-2.0%, P