PMID:
Nutr Cancer. 2019 Oct 22:1-11. Epub 2019 Oct 22. PMID: 31635496
Abstract Title:
Mexican hawthorn (J. B. Phipps) stems and leaves induce cell death on breast cancer cells.
Abstract:
Diverse molecules with cytotoxic activity against cancer cells have been isolated from the polar extracts of different parts of various hawthorn species that grow around the world. In Mexico, hawthorn () is popularly consumed, but its content of anticancer substances has never been evaluated. Because antitumor substances have been identified in polar and nonpolar extracts of many plants, we evaluated the cytotoxic activity against breast cancer cells of petroleum ether, ethanol, and water extracts of the leaves and stems of. In contrast to other hawthorn species that contain anti-tumor substances in polar extracts, the petroleum ether extract (but not the ethanol or water extracts) ofhad cytotoxic properties (IC