PMID:
Curr Mol Med. 2019 Oct 16. Epub 2019 Oct 16. PMID: 31622191
Abstract Title:
Curcumin activates the Nrf2 pathway and induces cellular protection against oxidative injury.
Abstract:
Curcumin is a naturally occurring polyphenol which is isolated from the rhizome of Curcuma longa (turmeric). This medicinal compound has different biological activities including antioxidant, antibacterial, antineoplastic, and anti-inflammation. It has also therapeutic effects for cancer, neurodegenerative disorders, renal disorders, and diabetes mellitus. Curcumin is safe and well-tolerated at high concentrations without making toxicity. In the present review, we demonstrated curcumin affects the Nrf2 signaling pathway to exert its therapeutic and biological activities.
Health Time 