PMID:
Toxicol Mech Methods. 2019 Nov ;29(9):710-722. Epub 2019 Aug 20. PMID: 31364915
Abstract Title:
Triggering of apoptosis and cell cycle arrest by fennel and clove oils in Caco-2 cells: the role of combination.
Abstract:
Fennel () and clove () oils are known for their various biological effects, including anticancer properties.To investigate the anticancer effect of combined fennel and clove oil treatment on Caco-2 cells and normal human lymphocytes (NHL).GC-MS,cytotoxicity, morphological, apoptosis-related marker, and flow cytometric cell cycle distribution analyses were conducted.Seventeen volatile compounds were identified in fennel oil, including-anethole (68.3%) and (+)-fenchone (8.1%). In clove oil, 22 compounds, including eugenol (71.4%) and caryophyllene (8.7%), were identified. ICof the fennel, clove, and oil mixture were 300 ± 5.0, 150 ± 4.0, and 73 ± 2.5 µg/mL, respectively with combination index (CI)
Health Time 