Acute effects of combined Bacopa, American ginseng and whole coffee fruit on working memory and cerebral haemodynamic response of the prefrontal cortex.

PMID: 

Nutr Neurosci. 2019 Nov 18:1-12. Epub 2019 Nov 18. PMID: 31736428

Abstract Title: 

Acute effects of combined Bacopa, American ginseng and whole coffee fruit on working memory and cerebral haemodynamic response of the prefrontal cortex: a double-blind, placebo-controlled study.

Abstract: 

This study assessed whether a multi-ingredient herbal supplement containing(BM),(PQ) and whole coffee fruit extract (WCFE) could enhance cognitive performance and cerebral-cortical activation during tasks of working memory and attention.In a randomised, double-blind, placebo-controlled, between-group study, 40 healthy adults between 18-60 years ( = 34.46 SD = 12.95) completed tasks of working memory and attention at baseline and 45 min post active or placebo supplement consumption. During the cognitive testing, changes in hemodynamic response in the prefrontal cortex (PFC) were continuously measured using functional near-infraredspectroscopy (fNIRS).Working memory task performance on the N-back task was significantly improved following active supplement consumption compared to placebo in terms of accuracy ( 

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