PMID:
J Cardiol. 2019 Dec 13. Epub 2019 Dec 13. PMID: 31839460
Abstract Title:
Long-term fine particulate matter exposure and cardiovascular mortality in the general population: a nationwide cohort study.
Abstract:
BACKGROUND: Although eastern Asian countries are exposed to high levels of air pollution, the impact of long-term exposures to fine particulate matter (PM) air pollution on all-cause and cardiovascular mortality is not well identified. We assessed the relationship between long-term PMexposure and all-cause/cardiovascular mortalities.METHODS: We included 436,933 subjects who received national health examinations from the Korean National Health Insurance Service-based National Sample Cohort. We matched subjects' residential-address areas with hourly-measurements of PMconcentration data. We estimated the risk of mortality with average PMexposure during the study period using a Cox proportional-hazards model.RESULTS: During 1,683,271 person·years, all-cause and cardiovascular mortalities were observed in 6432 and 1603 subjects (382 and 95 per 100,000 person·years, respectively). An increase in 10 μg/min PMwas associated with increases in all-cause and cardiovascular mortalities by 3.4 % [2.7-4.1] and 4.7 % [3.6-5.8], respectively (each p