PMID:
Vaccine. 2014 Dec 5 ;32(51):6948-6955. Epub 2014 Oct 30. PMID: 25444821
Abstract Title:
Maternal immunization with pneumococcal 9-valent conjugate vaccine and early infant otitis media.
Abstract:
A randomized trial of an investigational 9-valent pneumococcal conjugate vaccine (PCV-9) or placebo given to pregnant women during the last trimester to prevent early infant otitis media (OM) was conducted. All infants received Prevnar(®) at 2, 4, 6, and 12 months. Clinic and adverse event records were reviewed to identify OM. Variables significantly related to acute OM by age 6 months (p