Pentamers from the HPV viral capsid protein are shared with human protein. Alterations of these proteins are linked to arrhythmias, cardiovascular diseases, and sudden death.

PMID: 

Lupus. 2016 Apr ;25(4):339-42. Epub 2016 Feb 3. PMID: 26846691

Abstract Title: 

Postural Orthostatic Tachycardia Syndrome (POTS)–A novel member of the autoimmune family.

Abstract: 

Postural orthostatic tachycardia syndrome (POTS) is a heterogeneous disorder of the autonomic nervous system in which a change from the supine position to an upright position causes an abnormally large increase in heart rate or tachycardia (30 bpm within 10 min of standing or head-up tilt). This response is accompanied by a decrease in blood flow to the brain and hence a spectrum of symptoms associated with cerebral hypoperfusion. Many of these POTS-related symptoms are also observed in chronic anxiety and panic disorders, and therefore POTS is frequently under- and misdiagnosed.

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