Acute disseminated myelitis is a monophasic inflammatory demyelinating disorder with aggressive neurological deficits that usually follows viral infection or immunization.

PMID: 

PLoS One. 2011 ;6(8):e22766. Epub 2011 Aug 10. PMID: 21853047

Abstract Title: 

Comparative brain stem lesions on MRI of acute disseminated encephalomyelitis, neuromyelitis optica, and multiple sclerosis.

Abstract: 

BACKGROUND: Brain stem lesions are common in patients with acute disseminated encephalomyelitis (ADEM), neuromyelitis optica (NMO), and multiple sclerosis (MS).OBJECTIVES: To investigate comparative brain stem lesions on magnetic resonance imaging (MRI) among adult patients with ADEM, NMO, and MS.METHODS: Sixty-five adult patients with ADEM (n = 17), NMO (n = 23), and MS (n = 25) who had brain stem lesions on MRI were enrolled. Morphological features of brain stem lesions among these diseases were assessed.RESULTS: Patients with ADEM had a higher frequency of midbrain lesions than did patients with NMO (94.1% vs. 17.4%, P

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