PMID:
Complement Ther Med. 2018 Aug ;39:14-18. Epub 2018 May 15. PMID: 30012385
Abstract Title:
Association between dietary flavonoids intake and prostate cancer risk: A case-control study in Sicily.
Abstract:
OBJECTIVES: The aim of this study is to test the association between dietary flavonoids intake and prostate cancer (PCa) in a sample of southern Italian individuals.DESIGN: A population-based case-control study on the association between PCa and dietary factors was conducted from January 2015 to December 2016, in a single institution.SETTING: Patients with elevated PSA (Prostate Specific Antigen) and/or suspicion of PCa underwent transperineal prostate biopsy (≥12 cores). A total of 118 histopathological-verified PCa cases were collected and matched with controls, which were selected from a sample of 2044 individuals randomly recruited among the same reference population. Finally, a total of 222 controls were selected.MAIN OUTCOME MEASURES: Prevalence of PCa.RESULTS: Consumption of certain groups of flavonoids significantly differed between controls and cases, in particular: flavonols (63.36 vs 37.14 mg/d, P