PMID:
Int J Vitam Nutr Res. 2020 Jan 23:1-11. Epub 2020 Jan 23. PMID: 31971481
Abstract Title:
Lower serum levels of alpha tocopherol and lycopene is associated with higher pain and physical disability in subjects with primary knee osteoarthritis: A case-control study.
Abstract:
: We aimed to determine dietary intake and serum concentration ofα-tocopherol and lycopene in subjects with knee osteoarthritis (KOA) in relation to pain intensity and functional status and comparing them with healthy controls.: This case-control study was conducted among 35 patients with primary KOA and 35 matched healthy subjects selected using convenience sampling method. Dietary intakes of alpha-tocopherol and lycopene were estimated from 24-hour dietary records. Visual Analogue Scale (VAS) and Western Ontario and McMaster (WOMAC) index were used to assess the pain and functional status, respectively.: Serum concentrations of alpha-tocopherol ( = ) and lycopene ( = ) were significantly lower in OA patients in comparison with healthy controls. Dietary intake of alpha-tocopherol was negatively associated with total WOMAC score ( = = ) and pain ( = = ) and physical function ( = = ) subscales. Dietary intake of lycopene was negatively associated with total WOMAC score ( =