These results indicate the potential usefulness of L. plantarum FB-T9 as a probiotic for the prevention and treatment of caries.

PMID: 

J Oral Microbiol. 2020 ;12(1):1703883. Epub 2019 Dec 25. PMID: 32002130

Abstract Title: 

Inhibitory and preventive effects ofFB-T9 on dental caries in rats.

Abstract: 

is recognized as the main cause of dental caries, and the formation of a plaque biofilm is required for caries development. This study aimed to determine the inhibitory effect ofFB-T9 onbiofilm formationand on the prevention and treatment of dental caries in rats. Duringexperiments, FB-T9 exhibited good bacteriostatic ability in a plate competition assay. This strain also significantly reduced the biomass and viability ofbiofilms and induced structural damage during the early (6 h), middle (12 h) and late (24 h) stages of biofilm formation. In a 70-dayexperiment, FB-T9 significantly reduced the levels ofon the dental surfaces of rats by more than 2 orders of magnitude of the levels in the dental caries model group (p

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