Vitamin D status was inversely associated with risk of community-acquired pneumonia and sepsis hospitalization in a community-living adult population.

PMID: 

Nutrients. 2014 Jun 10 ;6(6):2196-205. Epub 2014 Jun 10. PMID: 24918697

Abstract Title: 

Vitamin D level and risk of community-acquired pneumonia and sepsis.

Abstract: 

Previous research has reported reduced serum 25-hydroxyvitamin D (25(OH)D) levels is associated with acute infectious illness. The relationship between vitamin D status, measured prior to acute infectious illness, with risk of community-acquired pneumonia (CAP) and sepsis has not been examined. Community-living individuals hospitalized with CAP or sepsis were age-, sex-, race-, and season-matched with controls. ICD-9 codes identified CAP and sepsis; chest radiograph confirmed CAP. Serum 25(OH)D levels were measured up to 15 months prior to hospitalization. Regression models adjusted for diabetes, renal disease, and peripheral vascular disease evaluated the association of 25(OH)D levels with CAP or sepsis risk. A total of 132 CAP patients and controls were 60± 17 years, 71% female, and 86% Caucasian. The 25(OH)D levels

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