PMID:
Int J Med Sci. 2019 ;16(6):845-853. Epub 2019 Jun 2. PMID: 31337958
Abstract Title:
A Combination ofseeds andRhizome Extracts Improves Knee Joint Function and Alleviates Pain in Non-Arthritic Adults Following Physical Activity.
Abstract:
: Knee joint pain is the most common reason for physical disability which associates with age. TamaFlex(NXT15906F6) is a synergistic anti-inflammatory formulation which contains ethanol/aqueous extracts ofseeds and ethanol extract ofrhizome.: In a 90-day randomized, double-blind, placebo-controlled study, we evaluated efficacy of NXT15906F6 in relieving pain and improving joint function in non-arthritic adults. Ninety non-arthritic subjects who experienced knee pain and joint discomfort following a six-minute walk test (SMWT) and Stair climb test (SCT) participated in the present trial. Subjects received either 250 mg (n=30) or 400 mg (n=30) of NXT15906F6 or matched placebo (PL: n=30) daily for 90 days. Improvement from baseline six-minute walk distance (SMWD) in NXT15906F6 groups, compared with placebo (PL) was the primary outcome of the study.: At post-intervention, subjects in NXT15906F6-250 (p
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