PMID:
Prog Neuropsychopharmacol Biol Psychiatry. 2013 Jan 10 ;40:180-6. Epub 2012 Aug 29. PMID: 22960104
Abstract Title:
Coumarins from Angelica archangelica Linn. and their effects on anxiety-like behavior.
Abstract:
UNLABELLED: TRADITIONAL RELEVANCE: Angelica archangelica Linn. (Apiaceae) is an herb distributed in tropical and subtropical regions of the world. Both in Chinese and Indian system of medicine, it is used for nervous disorders including anxiety, anorexia, migraine and other cerebral diseases.AIM OF STUDY: To evaluate the anxiolytic potential of non polar coumarins isolated from A. archangelica Linn.METHODS AND RESULTS: A. archangelica Linn. (1 kg) was subjected to extraction in a soxhlet apparatus with petroleum ether (40-60°C), yield 6.9% w/w. The extract of petroleum ether produced a yellow colored precipitate (YP) which was evaluated for anxiolytic like effect using EPM test and was found significant (**P
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