PMID:
Cell Metab. 2020 Mar 3 ;31(3):445-447. PMID: 32130878
Abstract Title:
Microbiome Modulation of the Host Adaptive Immunity through Bile Acid Modification.
Abstract:
The microbiome is well known to influence the immune response of the host. Song et al. now show that the microbiome modulates adaptive immunity in mice through formation of bile acid species acting on RORγregulatory T cells via the Vitamin D Receptor, thereby lowering the vulnerability for chemically induced colitis.
Health Time 