PMID:
Crit Rev Food Sci Nutr. 2019 Aug 19:1-11. Epub 2019 Aug 19. PMID: 31423805
Abstract Title:
Curcumin for depression: a meta-analysis.
Abstract:
Curcumin is the principal curcuminoid found in turmeric (), a spice frequently used in Asian countries. Given its anti-inflammatory and antioxidant properties, it has been hypothesized that curcumin might be effective in treating symptoms of a variety of neuropsychiatric disorders, such as depression. We conducted a systematic review following the PRISMA guidelines. In August 2019, we screened 930 articles, of which 9 were eligible for the meta-analysis. In 7 articles, participants were affected by major depressive disorder (MDD), while in other two they suffered from depression secondary to a medical condition. We found an overall significant effect of curcumin on depressive (10 studies, 531 participants, Hedge's = -0.75, 95% CI -1.11 to -0.39,