PMID:
Int J Pharm. 2020 Jan 25 ;574:118916. Epub 2019 Dec 4. PMID: 31811927
Abstract Title:
CBD loaded microparticles as a potential formulation to improve paclitaxel and doxorubicin-based chemotherapy in breast cancer.
Abstract:
Cannabidiol (CBD) has emerged as a potential agent for breast cancer management. In this work, the potential use of cannabidiol in solution (CBD) and encapsulated in polymeric microparticles when combined with paclitaxel (PTX) and doxorubicin (DOX) in breast cancer treatment has been evaluated for the first time using MCF-7 and MDA-MB-231 cells. CBD, previously administered at suboptimal concentrations (cell death