PMID:
Mol Nutr Food Res. 2020 May 7:e1900922. Epub 2020 May 7. PMID: 32380577
Abstract Title:
Long-termβ-galacto-oligosaccharides Supplementation Decreases the Development of Obesity and Insulin Resistance in Mice Fed a Western-type Diet.
Abstract:
SCOPE: The gut microbiota might be a critical modifier of metabolic disease development. Dietary fibers such as galacto-oligosaccharides (GOS) presumably stimulate the growth of bacteria beneficial for metabolic health. This study aimed to assess the impact of GOS on obesity, glucose and lipid metabolism.METHODS & RESULTS: Following Western-type diet feeding (C57BL/6 mice) with or withoutβ-GOS (7% w/w, 15 weeks), body composition, glucose and insulin tolerance tests, lipid profiles, fat kinetics studies and microbiota analyses were performed. GOS reduced body weight gain (p
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