PMID: Int J Clin Pract. 2018 Jun ;72(6):e13211. Epub 2018 May 31. PMID: 29855123 Abstract Title: Low serum zinc level: The relationship with severe pneumonia and survival in critically ill children. Abstract: BACKGROUND: Zinc deficiency is common among children in developing countries; but, there is still conflicting evidence on whether the alteration in zinc metabolism …
Continue reading “Zinc has both a diagnostic and a prognostic value for children with pneumonia.”
PMID: Integr Cancer Ther. 2016 06 ;15(2):216-25. Epub 2016 Apr 28. PMID: 27125675 Abstract Title: Curcumol Suppresses Breast Cancer Cell Metastasis by Inhibiting MMP-9 Via JNK1/2 and Akt-Dependent NF-κB Signaling Pathways. Abstract: Curcumolhas been reported to possess antitumor activity. However, its effect and mechanisms against tumor metastasis are still unclear. This study is to investigate …
Continue reading “Curcumol suppresses breast cancer cell metastasis.”
PMID: Epilepsia. 2012 Nov ;53 Suppl 6:37-44. PMID: 23134494 Abstract Title: Blood-brain barrier dysfunction-induced inflammatory signaling in brain pathology and epileptogenesis. Abstract: The protection of the brain from blood-borne toxins, proteins, and cells is critical to the brain's normal function. Accordingly, a compromise in the blood-brain barrier (BBB) function accompanies many neurologic disorders, and is …
PMID: J Trop Pediatr. 2018 Dec 6. Epub 2018 Dec 6. PMID: 30521044 Abstract Title: Effects of Zinc Combined with Probiotics on Antibiotic-associated Diarrhea Secondary to Childhood Pneumonia. Abstract: Aim: The aim of this study was to evaluate the impact of zinc combined with probiotics (Bifico) on antibiotic-associated diarrhea (AAD) secondary to pneumonia.Methods: A total …
PMID: PLoS Pathog. 2019 Aug ;15(8):e1007957. Epub 2019 Aug 22. PMID: 31437249 Abstract Title: Dietary zinc and the control of Streptococcus pneumoniae infection. Abstract: Human zinc deficiency increases susceptibility to bacterial infection. Although zinc supplementation therapies can reduce the impact of disease, the molecular basis for protection remains unclear. Streptococcus pneumoniae is a major cause …
Continue reading “Dietary zinc and the control of Streptococcus pneumoniae infection.”
PMID: Zhongguo Zhong Xi Yi Jie He Za Zhi. 2016 10 ;36(10):1229-1234. PMID: 30641012 Abstract Title: [Effect of Curcumol on the Biological Behavior of Multiple Myeloma Cells]. Abstract: Objective To observe the effect of curcumol on the biological behavior of multiple myeloma (MM) cells, thus studying its possible mechanisms for MM treatment. Methods Bone marrow …
Continue reading “Effect of curcumol on the biological behavior of multiple myeloma cells.”
PMID: Med Sci Monit. 2017 Jan 31 ;23:555-562. Epub 2017 Jan 31. PMID: 28138126 Abstract Title: Curcumol Promotes Vascular Endothelial Growth Factor (VEGF)-Mediated Diabetic Wound Healing in Streptozotocin-Induced Hyperglycemic Rats. Abstract: BACKGROUND Wound healing in chronic diabetic mellitus is mainly associated with the management of angiogenesis. The angiogenic mechanism of vascular endothelial growth factor (VEGF) …
PMID: Mol Neurobiol. 2016 11 ;53(9):6078-6090. Epub 2015 Nov 4. PMID: 26537901 Abstract Title: Mechanisms of Mitochondrial Dysfunction in Alzheimer's Disease. Abstract: Mitochondria are the primary source for energy generation in the cell, which manifests itself in the form of the adenosine triphosphate (ATP). Nicotinamide dinucleotide (NADH) molecules are the first to enter the so-called …
PMID: J Alzheimers Dis. 2006 Jul ;9(2):155-66. PMID: 16873963 Abstract Title: Dysfunction of mitochondria and oxidative stress in the pathogenesis of Alzheimer's disease: on defects in the cytochrome c oxidase complex and aldehyde detoxification. Abstract: The mitochondrion is an organelle that plays a central role in energy production. It, at the same time, generates reactive …
PMID: J Agric Food Chem. 2017 Apr 12 ;65(14):3074-3082. Epub 2017 Mar 31. PMID: 28345336 Abstract Title: Proteomic Identification of eEF1A1 as a Molecular Target of Curcumol for Suppressing Metastasis of MDA-MB-231 Cells. Abstract: Curcumol, a major volatile component in Rhizoma Curcumae, exhibits a potent antimetastatic effect on breast cancer cells. However, its molecular mechanism …
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