Maternal vitamin B12 deficiency in rats alters DNA methylation in metabolically important genes in their offspring.

PMID:  Mol Cell Biochem. 2020 May ;468(1-2):83-96. Epub 2020 Mar 18. PMID: 32189172 Abstract Title:  Maternal vitamin Bdeficiency in rats alters DNA methylation in metabolically important genes in their offspring. Abstract:  Vitamin Bdeficiency is a critical problem worldwide and peri-conceptional deficiency of this vitamin is associated with the risk of complex cardio-metabolic diseases. Nutritional perturbations …

The prevalence of vitamin B12 deficiency is considerable among diabetic patients on metformin therapy.

PMID:  Sultan Qaboos Univ Med J. 2020 Feb ;20(1):e90-e94. Epub 2020 Mar 9. PMID: 32190375 Abstract Title:  Vitamin B12 Deficiency in Diabetic Patients on Metformin Therapy: A cross-sectional study from Oman. Abstract:  Objectives: This study aimed to determine the prevalence of vitamin B12 deficiency amongst diabetic patients on metformin therapy.Methods: This cross-sectional study was conducted …

Higher vitamin B12 level at Parkinson’s disease diagnosis is associated with lower risk of future dementia.

PMID:  Parkinsonism Relat Disord. 2020 Mar 16 ;73:19-22. Epub 2020 Mar 16. PMID: 32203914 Abstract Title:  Higher vitamin B12 level at Parkinson's disease diagnosis is associated with lower risk of future dementia. Abstract:  INTRODUCTION: To determine whether vitamin B12 level at Parkinson's disease (PD) diagnosis predicts time to develop dementia.METHODS: We utilized a population-based cohort …

Low vitamin B12 levels: An underestimated cause Of minimal cognitive impairment and dementia.

PMID:  Cureus. 2020 Feb 13 ;12(2):e6976. Epub 2020 Feb 13. PMID: 32206454 Abstract Title:  Low Vitamin B12 Levels: An Underestimated Cause Of Minimal Cognitive Impairment And Dementia. Abstract:  Background Vitamin B12 deficiency is linked to impaired cognition and memory along with a sensation of tingling and numbness, an outcome of poor myelination. Elevated methylmalonic acid …

Vitamin B12 regulates glial migration and synapse formation through isoform-specific control of PTP-3/LAR PRTP expression.

PMID:  Cell Rep. 2020 Mar 24 ;30(12):3981-3988.e3. PMID: 32209461 Abstract Title:  Vitamin B12 Regulates Glial Migration and Synapse Formation through Isoform-Specific Control of PTP-3/LAR PRTP Expression. Abstract:  Vitamin B12 is known to play critical roles during the development and aging of the brain, and vitamin B12 deficiency has been linked to neurodevelopmental and degenerative disorders. …

Vitamin B12 is neuroprotective in experimental pneumococcal meningitis.

PMID:  J Neuroinflammation. 2020 Apr 1 ;17(1):96. Epub 2020 Apr 1. PMID: 32238192 Abstract Title:  Vitamin Bis neuroprotective in experimental pneumococcal meningitis through modulation of hippocampal DNA methylation. Abstract:  BACKGROUND: Bacterial meningitis (BM) causes apoptotic damage to the hippocampus and homocysteine (Hcy) accumulation to neurotoxic levels in the cerebrospinal fluid of children. The Hcy pathway …

The results of this study indicated that intervention with vitamin B12 in pregnancy reduces possibilities of the onset of anemia.

PMID:  J Med Food. 2020 Apr 17. Epub 2020 Apr 17. PMID: 32302504 Abstract Title:  Vitamin B12 Supplementation in Addition to Folic Acid and Iron Improves Hematological and Biochemical Markers in Pregnancy: A Randomized Controlled Trial. Abstract:  Vitamin B12 plays an important role in cell division and is of vital importance during pregnancy. Iron and …

The results of the study show that vitamin B12 deficiency or insufficiency and elevated homocysteine may contribute to the etiopathogenesis of depression.

PMID:  Child Adolesc Ment Health. 2020 Apr 18. Epub 2020 Apr 18. PMID: 32304285 Abstract Title:  The relationship of severity of depression with homocysteine, folate, vitamin B12, and vitamin D levels in children and adolescents. Abstract:  BACKGROUND: Depression is a heterogeneous disorder and is thought to develop as a result of complex interactions between genetic …

Anti-obesity effects of a mixed extract containing Platycodon grandiflorum, Apium graveolens and green tea.

PMID:  Exp Ther Med. 2020 Apr ;19(4):2783-2791. Epub 2020 Feb 5. PMID: 32256761 Abstract Title:  Anti-obesity effects of a mixed extract containingand green tea in high-fat-diet-induced obese mice. Abstract:  The anti-obesity effect of a combination of extracts made of(PGE),(AGE) and green tea (GTE) extracts was investigated in a high-fat diet-induced obese C57BL/6N mouse model. Body …

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