Aluminum nanoparticles are more neurotoxic than micrometer aluminum.

PMID:  Biol Trace Elem Res. 2018 Jun ;183(2):261-269. Epub 2017 Aug 30. PMID: 28856594 Abstract Title:  Size-Dependent Neurotoxicity of Aluminum Oxide Particles: a Comparison Between Nano- and Micrometer Size on the Basis of Mitochondrial Oxidative Damage. Abstract:  Aluminum nanoparticles (AlNPs) are among the most abundantly produced nanosized particles in the market. There is limited information …

This study outlines aluminum’s dose-dependent cardiotoxic effects.

PMID:  Environ Pollut. 2018 Nov ;242(Pt A):814-826. Epub 2018 Jul 17. PMID: 30032078 Abstract Title:  Aluminum: A potentially toxic metal with dose-dependent effects on cardiac bioaccumulation, mineral distribution, DNA oxidation and microstructural remodeling. Abstract:  Large amounts of aluminum (Al) are found in wastewater from industrial bauxite mining, which is often responsible for the contamination of …

Saffron could be an effective intervention for symptoms of depression and anxiety.

PMID:  Nutr Rev. 2019 May 28. Epub 2019 May 28. PMID: 31135916 Abstract Title:  Effect of saffron supplementation on symptoms of depression and anxiety: a systematic review and meta-analysis. Abstract:  CONTEXT: Saffron (Crocus sativus L.) has gained interest as a potential treatment in psychiatry.OBJECTIVE: This systematic review and meta-analysis sought to investigate the effect of …

The findings of this study showed that saffron administration was well comparable with fluoxetine and placebo.

PMID:  Psychol Res Behav Manag. 2019 ;12:297-305. Epub 2019 Apr 23. PMID: 31118846 Abstract Title:  The efficacy of(Saffron) versus placebo and Fluoxetine in treating depression: a systematic review and meta-analysis. Abstract:  Depression represents a serious public health concern, imposing a high burden, both in epidemiological and clinical terms.(Saffron) is a herbal remedy that has anti-cancer, …

A subgroup of patients with mitochondrial disease may be at risk of autistic regression with fever.

PMID:  J Child Neurol. 2010 Apr ;25(4):429-34. Epub 2009 Sep 22. PMID: 19773461 Abstract Title:  Fever plus mitochondrial disease could be risk factors for autistic regression. Abstract:  Autistic spectrum disorders encompass etiologically heterogeneous persons, with many genetic causes. A subgroup of these individuals has mitochondrial disease. Because a variety of metabolic disorders, including mitochondrial disease …

The protective role of hawthorn fruit extract against high salt-induced hypertension.

PMID:  Food Funct. 2019 Feb 20 ;10(2):849-858. PMID: 30681096 Abstract Title:  The protective role of hawthorn fruit extract against high salt-induced hypertension in Dahl salt-sensitive rats: impact on oxidative stress and metabolic patterns. Abstract:  In the present study, the renal-protective effect of hawthorn fruit extract (HW) on high-salt hypertension and its effect on metabolic patterns …

Beneficial cardiovascular effects of hydroalcoholic extract from Crocus sativus in hypertension induced by angiotensin II.

PMID:  J Pharmacopuncture. 2019 Jun ;22(2):95-101. Epub 2019 Jun 30. PMID: 31338249 Abstract Title:  Beneficial Cardiovascular Effects of Hydroalcoholic Extract from Crocus Sativus in Hypertension Induced by Angiotensin II. Abstract:  Objectives: Angiotensin II (AngII), a major product of renin-angiotensin system (RAS) has important role in induction of hypertension and antihypertensive effect of several medicinal plant …

This report shows that daily supplementation with 100 mg C. sativus powder improved systolic blood pressure.

PMID:  Avicenna J Phytomed. 2019 Jul-Aug;9(4):322-333. PMID: 31309071 Abstract Title:  The effect of saffron (L.) supplementation on blood pressure, and renal and liver function in patients with type 2 diabetes mellitus: A double-blinded, randomized clinical trial. Abstract:  Objective: Microalbuminuria and hypertension are the risk factors for diabetic nephropathy, and increased levels of liver enzymes are …

Saffron could be added to sport beverages and supplements to enhance an athlete’s performance.

PMID:  J Food Biochem. 2019 Aug ;43(8):e12946. Epub 2019 Jun 20. PMID: 31368566 Abstract Title:  Effect of saffron (Crocus sativus L.) and endurance training on mitochondrial biogenesis, endurance capacity, inflammation, antioxidant, and metabolic biomarkers in Wistar rats. Abstract:  We aimed to evaluate the effect of saffron (Crocus Sativus L.) treatment on endurance capacity, mitochondrial biogenesis, …

Curcumin ameliorated myocardial infarction by inhibition of cardiotoxicity.

PMID:  J Cell Biochem. 2019 Feb 18. Epub 2019 Feb 18. PMID: 30775806 Abstract Title:  Curcumin ameliorated myocardial infarction by inhibition of cardiotoxicity in the rat model. Abstract:  Cardiovascular diseases are the main cause of death globally. Many attempts have been done to ameliorate the pathological changes after the occurrence of myocardial infarction. Curcumin is …

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