PMID: Anticancer Agents Med Chem. 2019 Jul 29. Epub 2019 Jul 29. PMID: 31362681 Abstract Title: Quercetin Promotes Cell Cycle Arrest and Apoptosis and Attenuates the Proliferation of Human Chronic Myeloid Leukemia Cell Line-K562 Through Interaction with HSPs (70 and 90), MAT2A and FOXM1. Abstract: BACKGROUND: Chronic Myeloid Leukaemia (CML) starts in certain blood-forming cells …
Author Archives: Taylor Mercado
Quercetin modulates signaling pathways and induces apoptosis in cervical cancer cells.
PMID: Biosci Rep. 2019 Aug 30 ;39(8). Epub 2019 Aug 13. PMID: 31366565 Abstract Title: Quercetin modulates signaling pathways and induces apoptosis in cervical cancer cells. Abstract: Cancer cells have the unique ability to overcome natural defense mechanisms, undergo unchecked proliferation and evade apoptosis. While chemotherapeutic drugs address this, they are plagued by a long …
Quercetin has therapeutic potential in the treatment of sepsis.
PMID: Med Sci Monit. 2019 Aug 4 ;25:5795-5800. Epub 2019 Aug 4. PMID: 31377749 Abstract Title: Quercetin Exerted Protective Effects in a Rat Model of Sepsis via Inhibition of Reactive Oxygen Species (ROS) and Downregulation of High Mobility Group Box 1 (HMGB1) Protein Expression. Abstract: BACKGROUND Sepsis is a severe medical condition. Approximately 0.75 million …
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Wild blueberry extracts can attenuate doxorubicin-induced damage to H9c2 cardiomyocytes.
PMID: Can J Physiol Pharmacol. 2019 Jul 31:1-5. Epub 2019 Jul 31. PMID: 31365282 Abstract Title: Blueberry extract attenuates doxorubicin-induced damage in H9c2 cardiac cells. Abstract: The objective of this study was to analyze the cardioprotective roles of 3 wild blueberry genotypes and one commercial blueberry genotype by measuring markers of oxidative stress and cell …
Cinnamaldehyde ameliorates high-glucose-induced oxidative stress and cardiomyocyte injury.
PMID: J Cardiovasc Pharmacol. 2019 Jul ;74(1):30-37. PMID: 31274840 Abstract Title: Cinnamaldehyde Ameliorates High-Glucose-Induced Oxidative Stress and Cardiomyocyte Injury Through Transient Receptor Potential Ankyrin 1. Abstract: Oxidative stress plays a critical role in diabetic cardiomyopathy. Transient receptor potential ankyrin subtype 1 (TRPA1) has antioxidative property. In this study, we tested whether activation of TRPA1 with …
Cinnamaldehyde enhances apoptotic effect of oxaliplatin and reverses epithelial-mesenchymal transition and stemnness in hypoxic colorectal cancer cells.
PMID: Exp Cell Res. 2019 Jul 12:111500. Epub 2019 Jul 12. PMID: 31306656 Abstract Title: Cinnamaldehyde enhances apoptotic effect of oxaliplatin and reverses epithelial-mesenchymal transition and stemnness in hypoxic colorectal cancer cells. Abstract: Oxaliplatin has been widely applied in clinical tumor chemotherapy, the treatment failure of which mainly blames on low susceptibility resulted from intrinsic …
Protective effect of cinnamon against acetaminophen-mediated cellular damage and apoptosis in renal tissue.
PMID: Environ Sci Pollut Res Int. 2019 Jan ;26(1):240-249. Epub 2018 Nov 3. PMID: 30392171 Abstract Title: Protective effect of cinnamon against acetaminophen-mediated cellular damage and apoptosis in renal tissue. Abstract: Acetaminophen, APAP, is a common over-the-counter drug with antipyretic-analgesic action. When APAP is used in large doses, it causes hepatotoxicity and nephrotoxicity but safe …
Cortical tau burden and behavioural dysfunctions in mice exposed to monosodium glutamate in early life.
PMID: PLoS One. 2019 ;14(8):e0220720. Epub 2019 Aug 14. PMID: 31412065 Abstract Title: Cortical tau burden and behavioural dysfunctions in mice exposed to monosodium glutamate in early life. Abstract: Although monosodium glutamate (MSG)-induced neurotoxicity has been recognized for decades, the potential similarities of the MSG model to Alzheimer's disease (AD)-type neuropathology have only recently been …
Combination of vitamin C and n-3 PUFA effectively reduces post-operative fatigue among patients who undergo coronary artery bypass graft surgery.
PMID: J Complement Integr Med. 2019 Aug 21. Epub 2019 Aug 21. PMID: 31433781 Abstract Title: The combined effect of vitamin C and omega-3 polyunsaturated fatty acids on fatigue following coronary artery bypass graft surgery: a triple-blind clinical trial. Abstract: Background Fatigue is a common compliant among patients who undergo coronary artery bypass graft (CABG) …
Vitamin C can modify the pathological and biochemical changes induced by MSG.
PMID: Int J Reprod Biomed (Yazd). 2019 Apr ;17(4). Epub 2019 May 28. PMID: 31435603 Abstract Title: Effects of monosodium glutamate on apoptosis of germ cells in testicular tissue of adult rat: An experimental study. Abstract: Background: Monosodium glutamate (MSG) is used as a flavoring and food seasoning. Some studies have reported the oxidative effects …
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