Epidemiological data is important for understanding the complex interplay of variables but insufficient to establish non-toxicity for infants and young children still receiving thimerosal-containing vaccines.

PMID:  Clin Chim Acta. 2010 Nov 11 ;411(21-22):1580-6. Epub 2010 Jul 16. PMID: 20638374 Abstract Title:  Making sense of epidemiological studies of young children exposed to thimerosal in vaccines. Abstract:  OBJECTIVE: To compare epidemiological studies dealing with neurological issues (compatible with Hg toxicity) linked to exposing newborns and infants to intramuscular doses of preservative-Hg resulting …

Kaempferol improves TRAIL-Mediated apoptosis in leukemia MOLT-4 cells.

PMID:  Anticancer Agents Med Chem. 2019 Jul 31. Epub 2019 Jul 31. PMID: 31364517 Abstract Title:  Kaempferol improves TRAIL-Mediated apoptosis in leukemia MOLT-4 cells by inhibition of anti-apoptotic proteins and promotion of death receptors expression. Abstract:  INTRODUCTION: Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL or Apo2L) is a member of the tumor necrosis factor (TNF) superfamily, …

Breastfed infants in Brazil receiving a full recommended schedule of immunizations showed an exceedingly high exposure of Al (225 to 1750 μg per dose) when compared with estimated levels absorbed from breast milk.

PMID:  J Expo Sci Environ Epidemiol. 2010 Nov ;20(7):598-601. Epub 2009 Dec 16. PMID: 20010978 Abstract Title:  Infants' exposure to aluminum from vaccines and breast milk during the first 6 months. Abstract:  The success of vaccination programs in reducing and eliminating infectious diseases has contributed to an ever-increasing number of vaccines given at earlier ages …

Kaempferol attenuates neuroinflammation and blood brain barrier dysfunction to improve neurological deficits in cerebral ischemia/reperfusion.

PMID:  Brain Res. 2019 Aug 1:146361. Epub 2019 Aug 1. PMID: 31377105 Abstract Title:  Kaempferol attenuates neuroinflammation and blood brain barrier dysfunction to improve neurological deficits in cerebral ischemia/reperfusion rats. Abstract:  Kaempferol has been reported to act as an anti-inflammation agent in LPS-induced neuroinflammation in vitro and in vivo, but its role in the inflammation …

Metal ingestion produced two of the hallmark characteristics of autism: social avoidance and a male-oriented bias in prairie vole.

PMID:  Behav Brain Res. 2010 Nov 12 ;213(1):42-9. Epub 2010 Apr 28. PMID: 20433873 Abstract Title:  Chronic metals ingestion by prairie voles produces sex-specific deficits in social behavior: an animal model of autism. Abstract:  We examined the effects of chronic metals ingestion on social behavior in the normally highly social prairie vole to test the …

Kaempferol attenuates imiquimod-induced psoriatic skin inflammation in a mouse model.

PMID:  Clin Exp Immunol. 2019 Aug 13. Epub 2019 Aug 13. PMID: 31407330 Abstract Title:  Kaempferol attenuates imiquimod-induced psoriatic skin inflammation in a mouse model. Abstract:  Psoriasis is an immune-mediated inflammatory skin disease that mainly affects the skin barrier. Treatment for psoriasis mainly includes conventional immunosuppressive drugs. However, long-term treatment with global immunosuppressive agents may …

Kaempferol exerts anti-proliferative effects on human ovarian cancer cells.

PMID:  J BUON. 2019 May-Jun;24(3):975-981. PMID: 31424650 Abstract Title:  Kaempferol exerts anti-proliferative effects on human ovarian cancer cells by inducing apoptosis, G0/G1 cell cycle arrest and modulation of MEK/ERK and STAT3 pathways. Abstract:  PURPOSE: Ovarian cancer causes significant mortality in women and is one of the most prevalent types of gynaecological cancer world over. Ovarian …

Rebalancing of the gut flora and microbial metabolism is responsible for the anti-arthritis effect of kaempferol.

PMID:  Acta Pharmacol Sin. 2019 Aug 19. Epub 2019 Aug 19. PMID: 31427695 Abstract Title:  Rebalancing of the gut flora and microbial metabolism is responsible for the anti-arthritis effect of kaempferol. Abstract:  Kaempferol is a natural flavonol that possesses various pharmacological activities, including anti-arthritis effects, yet the underlying mechanisms remain controversial. To evaluate the anti-arthritis …

These findings suggested that kaempferol might be regarded as a bioactive food ingredient to prevent oxidative damage and treat bladder cancer.

PMID:  Molecules. 2018 Oct 10 ;23(10). Epub 2018 Oct 10. PMID: 30309003 Abstract Title:  Kaempferol Attenuates ROS-Induced Hemolysis and the Molecular Mechanism of Its Induction of Apoptosis on Bladder Cancer. Abstract:  Bladder cancer has become the most common malignant urinary carcinoma. Studies have shown that significant antioxidant and bladder cancer-fighting properties of several plant-based diets …

The hydroalcoholic extract of the Psidium guajava fruit prevented ovariectomized-induced bone loss in animals.

PMID:  Iran J Med Sci. 2018 Nov ;43(6):623-632. PMID: 30510339 Abstract Title:  Effects of the Hydroalcoholic Extract of theFruit on Osteoporosis Prevention in Ovariectomized Rats. Abstract:  Background: Several plants have been shown to possess antioxidant and estrogenic properties that can be useful in postmenopausal bone-loss prevention. The present study aimed to investigate the anti-osteoporotic effects …

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