Taylor Mercado

Fucoidan immobilized at the surface of a fibrous mesh presents toxic effects over melanoma cells, but not over non-cancer skin cells.

PMID: Biomacromolecules. 2020 May 18. Epub 2020 May 18. PMID: 32421313 Abstract Title: Fucoidan immobilized at the surface of a fibrous mesh presents toxic effects over melanoma cells, but not over non-cancer skin cells. Abstract: The use of fucoidan, a marine-origin bioactive polymer, is herein proposed as a component of an innovative and effective strategy …

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Fucoidan could be implemented as a beneficial antioxidant agent.

PMID: Molecules. 2020 May 19 ;25(10). Epub 2020 May 19. PMID: 32438702 Abstract Title: Protective Effects of Fucoidan Isolated from Celluclast-Assisted Extract ofSporophylls against AAPH-Induced Oxidative Stress In Vitro and In Vivo Zebrafish Model. Abstract: Fucoidan is a fucose-enriched polysaccharide, obtained from brown algae, with demonstrated antioxidant properties. However, traditional extraction methods using water or …

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Can Walking Barefoot Heal Your Heart?

Originally published on www.thesacredscience.com Why do so many people equate relaxation and pleasure with walking barefoot along the beach as the waves roll in? How come my son River’s first instinct is to take his shoes off when he sees a field of green grass? Is it kooky human behavior that is simply hard-wired into our …

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Fucoxanthin alleviates palmitate-induced inflammation in RAW 264.7 cells through improving lipid metabolism and attenuating mitochondrial dysfunction.

PMID: Food Funct. 2020 Apr 30 ;11(4):3361-3370. PMID: 32232236 Abstract Title: Fucoxanthin alleviates palmitate-induced inflammation in RAW 264.7 cells through improving lipid metabolism and attenuating mitochondrial dysfunction. Abstract: In this study, we aimed to examine the effects of fucoxanthin on inflammation triggered by palmitate in macrophages. Raw 264.7 cells were treated with palmitate with or …

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Fucoxanthin ameliorates atopic dermatitis symptoms by regulating keratinocytes and regulatory innate lymphoid cells.

PMID: Int J Mol Sci. 2020 Mar 22 ;21(6). Epub 2020 Mar 22. PMID: 32235696 Abstract Title: Fucoxanthin Ameliorates Atopic Dermatitis Symptoms by Regulating Keratinocytes and Regulatory Innate Lymphoid Cells. Abstract: Fucoxanthin (FX) is a xanthophyll that is contained abundantly in marine plants. The biological action of FX includes its antioxidant and anti-lipogenic activities, while …

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Spent hops extract as modulator of the inflammatory response in lipopolysaccharide stimulated RAW 264.7 macrophages.

PMID: J Physiol Pharmacol. 2020 Feb ;71(1). Epub 2020 Apr 27. PMID: 32350150 Abstract Title: Spent hops (Humulus Lupulus L.) extract as modulator of the inflammatory response in lipopolysaccharide stimulated RAW 264.7 macrophages. Abstract: Macrophages play important roles in acute and chronic inflammation. Upon their activation, they secrete a variety of mediators, including eicosanoids, nitric …

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Anti-rheumatic activity of phenethyl isothiocyanate via inhibition of histone deacetylase-1.

PMID: Chem Biol Interact. 2020 Jun 1 ;324:109095. Epub 2020 Apr 11. PMID: 32289289 Abstract Title: Anti-rheumatic activity of Phenethyl isothiocyanate via inhibition of histone deacetylase-1. Abstract: Rheumatoid Arthritis (RA) affects approximately 1% of the total world population. Despite incessant research and development of new therapeutic agents, management of RA is still a troublesome affair. …

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β-phenethyl isothiocyanate induces cell death in human osteosarcoma.

PMID: Oxid Med Cell Longev. 2020 ;2020:5021983. Epub 2020 Apr 4. PMID: 32322335 Abstract Title: -Phenethyl Isothiocyanate Induces Cell Death in Human Osteosarcoma through Altering Iron Metabolism, Disturbing the Redox Balance, and Activating the MAPK Signaling Pathway. Abstract: Osteosarcoma is the most common primary malignancy of the skeleton in children and adults. The outcomes of …

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Xanthohumol protects neuron from cerebral ischemia injury in experimental stroke.

PMID: Mol Biol Rep. 2020 Apr ;47(4):2417-2425. Epub 2020 Feb 27. PMID: 32108303 Abstract Title: Xanthohumol protects neuron from cerebral ischemia injury in experimental stroke. Abstract: Treatment of antioxidants is necessary to protect ischemic stroke associated neuronal damage. Xanthohumol (XN), a natural flavonoid extracted from hops, has been reported to have potential function as an …

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Xanthohumol induces DNA damages in colorectal cancer cells and sensitizes SW480 cells to the SN38 chemotherapeutic agent.

PMID: Cells. 2020 Apr 10 ;9(4). Epub 2020 Apr 10. PMID: 32290112 Abstract Title: Xanthohumol, a Prenylated Flavonoid from Hops, Induces DNA Damages in Colorectal Cancer Cells and Sensitizes SW480 Cells to the SN38 Chemotherapeutic Agent. Abstract: In spite of chemotherapy and systematic screening for people at risk, the mortality rate of colorectal cancer (CRC) …

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