Taylor Mercado

Western diet and the immune system: An inflammatory connection.

PMID: Immunity. 2019 11 19 ;51(5):794-811. PMID: 31747581 Abstract Title: Western Diet and the Immune System: An Inflammatory Connection. Abstract: The consumption of Western-type calorically rich diets combined with chronic overnutrition and a sedentary lifestyle in Western societies evokes a state of chronic metabolic inflammation, termed metaflammation. Metaflammation contributes to the development of many prevalent …

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The impact of dietary components on regulatory T cells and disease.

PMID: Front Immunol. 2020 ;11:253. Epub 2020 Feb 21. PMID: 32153577 Abstract Title: The Impact of Dietary Components on Regulatory T Cells and Disease. Abstract: The rise in the prevalence of autoimmune diseases in developed societies has been associated with a change in lifestyle patterns. Among other factors, increased consumption of certain dietary components, such …

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Consumption of the total Western diet promotes colitis and inflammation-associated colorectal cancer in mice.

PMID: Nutrients. 2020 Feb 20 ;12(2). Epub 2020 Feb 20. PMID: 32093192 Abstract Title: Consumption of the Total Western Diet Promotes Colitis and Inflammation-Associated Colorectal Cancer in Mice. Abstract: Consumption of a Western type diet is a known risk factor for colorectal cancer. Our group previously developed the total Western diet (TWD) for rodents with …

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Lactobacillus Brevis OPK-3 from kimchi prevents obesity and modulates the expression of adipogenic and pro-inflammatory genes.

PMID: Nutrients. 2020 Feb 26 ;12(3). Epub 2020 Feb 26. PMID: 32110872 Abstract Title: OPK-3 from Kimchi Prevents Obesity and Modulates the Expression of Adipogenic and Pro-Inflammatory Genes in Adipose Tissue of Diet-Induced Obese Mice. Abstract: Our previous study reported that lactic acid bacteria (OPK-3) isolated from kimchi ameliorated intracellular lipid accumulation in 3T3-L1 adipocyte. …

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Effects of novel probiotics in a murine model of irritable bowel syndrome.

PMID: Korean J Gastroenterol. 2020 Mar 25 ;75(3):141-146. PMID: 32209802 Abstract Title: Effects of Novel Probiotics in a Murine Model of Irritable Bowel Syndrome. Abstract: Background/Aims: Dysbiosis is an important factor in the pathogenesis of irritable bowel syndrome (IBS). Several studies have reported promising results using probiotics for the treatment of IBS. This study evaluated …

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The role of beneficial bacteria wall elasticity in regulating innate immune response.

PMID: EPMA J. 2015 ;6(1):13. Epub 2015 Jun 19. PMID: 26110044 Abstract Title: The role of beneficial bacteria wall elasticity in regulating innate immune response. Abstract: BACKGROUND: Probiotics have great potential to contribute to development of healthy dietary regimes, preventive care, and an integrated approach to immunity-related disease management. The bacterial wall is a dynamic …

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Th17 cells as potential probiotic therapeutic targets in Inflammatory bowel diseases.

PMID: Int J Mol Sci. 2015 Sep 1 ;16(9):20841-58. Epub 2015 Sep 1. PMID: 26340622 Abstract Title: Th17 Cells as Potential Probiotic Therapeutic Targets in Inflammatory Bowel Diseases. Abstract: Inflammatory bowel diseases (IBD) are characterized by wasting and chronic intestinal inflammation triggered by various cytokine-mediated pathways. In recent years, it was shown that T helper …

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The role of gut microbiota in the regulation of the immune response.

PMID: Rev Med Chil. 2016 Jul ;144(7):910-6. PMID: 27661555 Abstract Title: [The role of gut microbiota in the regulation of the immune response]. Abstract: The gastrointestinal tract hosts around 10(14) bacterial microorganisms, in a constantly growing density from the stomach to the distal colon. This microbiota is composed by more than 500 species of bacteria, …

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Lactobacillus rhamnosus Lcr35 as an effective treatment for preventing Candida albicans infection.

PMID: PLoS One. 2019 ;14(11):e0216184. Epub 2019 Nov 6. PMID: 31693670 Abstract Title: Lactobacillus rhamnosus Lcr35 as an effective treatment for preventing Candida albicans infection in the invertebrate model Caenorhabditis elegans: First mechanistic insights. Abstract: The increased recurrence of Candida albicans infections is associated with greater resistance to antifungal drugs. This involves the establishment of …

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Immunomodulatory properties of Lactobacillus plantarum NC8 expressing an anti-CD11c single-chain Fv fragment.

PMID: J Microbiol Biotechnol. 2019 Jan 28 ;29(1):160-170. PMID: 30415527 Abstract Title: Immunomodulatory Properties ofNC8 Expressing an Anti-CD11c Single-Chain Fv Fragment. Abstract: The lactic acid bacteria species() has been used extensively for vaccine delivery. Considering to the critical role of dendritic cells in stimulating host immune response, in this study, we constructed a novel CD11c-targetingstrain …

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