Author Archives: Taylor Mercado

PMID:  J Neuroimmune Pharmacol. 2019 Jul 18. Epub 2019 Jul 18. PMID: 31321663 Abstract Title:  Neuroprotective Effects of Genistein in a SOD1-G93A Transgenic Mouse Model of Amyotrophic Lateral Sclerosis. Abstract:  Oxidant toxicity has been implicated in the pathogenesis of amyotrophic lateral sclerosis (ALS), an insidiously progressive neurodegenerative disorder involving upper and lower motor neurons. Here, …

Continue reading “Genistein could be a promising treatment for human amyotrophic lateral sclerosis.”

PMID:  J Food Drug Anal. 2018 04 ;26(2):761-768. Epub 2017 Nov 10. PMID: 29567247 Abstract Title:  Antibacterial activity of propolins from Taiwanese green propolis. Abstract:  Taiwanese green propolis is a prenylated flavonoid rich honeybee product and propolins isolated from Taiwanese green propolis exert a broad spectrum of biological activities, such as anti-cancer and anti-oxidant. However, …

Continue reading “Antibacterial activity of propolins from Taiwanese green propolis.”

PMID:  Front Immunol. 2019 ;10:936. Epub 2019 May 1. PMID: 31118933 Abstract Title:  Naringenin Produces Neuroprotection Against LPS-Induced Dopamine Neurotoxicity via the Inhibition of Microglial NLRP3 Inflammasome Activation. Abstract:  Parkinson's disease (PD) is the second most prevalent central nervous system (CNS) degenerative disease and characterized by slow and progressive loss of dopamine (DA) neurons in …

Continue reading “These findings suggest naringenin might hold a promising therapeutic potential for Parkinson’s disease.”

PMID:  Int J Med Sci. 2019 ;16(5):644-653. Epub 2019 May 7. PMID: 31217731 Abstract Title:  Naringenin Ameliorates Renovascular Hypertensive Renal Damage by Normalizing the Balance of Renin-Angiotensin System Components in Rats. Abstract:  Naringenin, a member of the dihydroflavone family, has been shown to have a protective function in multiple diseases. We previously demonstrated that naringenin …

Continue reading “Naringenin attenuated renal damage in a rat model of renovascular hypertension.”

n/a PMID:  J Nat Med. 2019 Jun 19. Epub 2019 Jun 19. PMID: 31218550 Abstract Title:  Naringenin suppresses neutrophil infiltration into adipose tissue in high-fat diet-induced obese mice. Abstract:  Recruitment of immune cells to adipose tissue is altered dramatically in obesity, which results in chronic inflammation of the adipose tissue that leads to metabolic disorders, …

Continue reading “Naringenin suppresses neutrophil infiltration into adipose tissue in high-fat diet-induced obese mice.”

PMID:  J Nutr Biochem. 2019 Aug ;70:215-226. Epub 2019 May 21. PMID: 31252288 Abstract Title:  Naringenin ameliorates progression of endometriosis by modulating Nrf2/Keap1/HO1 axis and inducing apoptosis in rats. Abstract:  Endometriosis is mainly characterized by the presence of endometrial tissue exterior to the uterus, however, the exact pathophysiology of this disease still remains uncertain. Moreover, …

Continue reading “naringenin may have a therapeutic potential in the treatment of endometriosis via induction of ROS-mediated apoptosis and its anti-invasive effects.”

PMID:  Mol Nutr Food Res. 2019 Jul 25:e1900224. Epub 2019 Jul 25. PMID: 31343820 Abstract Title:  Anti-Diabetic, Anti-Inflammatory, and Anti-Oxidant Effects of Naringenin in an In Vitro Human Model and an In Vivo Murine Model of Gestational Diabetes Mellitus. Abstract:  SCOPE: Gestational diabetes mellitus (GDM), which affects up to 20% of pregnant women, is associated …

Continue reading “Naringenin is shown to improve insulin sensitivity, inflammation, and oxidative stress associated with gestational diabetes mellitus.”

PMID:  J Food Biochem. 2019 Jul ;43(7):e12885. Epub 2019 May 7. PMID: 31353690 Abstract Title:  Erectile dysfunction attenuation by naringenin in streptozotocin-induced diabetic rats. Abstract:  Diabetes mellitus is associated with sexual dysfunction, which leads to infertility in animal models. The aim of this study was to evaluate sexual behavior in diabetic rats administered with naringenin. …

Continue reading “Erectile dysfunction attenuation by naringenin in streptozotocin-induced diabetic rats.”

PMID:  Environ Toxicol Pharmacol. 2019 Jul 23 ;71:103224. Epub 2019 Jul 23. PMID: 31376681 Abstract Title:  Neuroprotective role of naringenin against methylmercury induced cognitive impairment and mitochondrial damage in a mouse model. Abstract:  Human exposure to organomercurials like methylmercury (MeHg) may occur by consumption of contaminated seafood, affecting various vital organs especially, brain contributing to …

Continue reading “Neuroprotective role of naringenin against methylmercury induced cognitive impairment and mitochondrial damage.”

PMID:  Cell Mol Biol (Noisy-le-grand). 2019 Jun 30 ;65(5):38-42. Epub 2019 Jun 30. PMID: 31304904 Abstract Title:  Naringin inhibits lipopolysaccharide-induced activation of microglia cells. Abstract:  The purpose of this study was to investigate the effect of naringin on lipopolysaccharide (LPS)-induced activation of BV2 microglia and inflammatory factor release, and the mechanism involved. Different concentrations of …

Continue reading “Naringin inhibits lipopolysaccharide-induced activation of microglia cells.”