Naringin may possess novel therapeutic potential for protection against LPS-induced myocardial dysfunction.

PMID:  Int Immunopharmacol. 2019 Jul 31 ;75:105782. Epub 2019 Jul 31. PMID: 31376623 Abstract Title:  Naringin mitigates myocardial strain and the inflammatory response in sepsis-induced myocardial dysfunction through regulation of PI3K/AKT/NF-κB pathway. Abstract:  Sepsis-induced myocardial dysfunction (SIMD) is a manifestation of severe sepsis and is the main cause of increased mortality in sepsis patients. Naringin …

Genistein inhibits nasopharyngeal cancer stem cells through sonic hedgehog signaling.

PMID:  Phytother Res. 2019 Jul 24. Epub 2019 Jul 24. PMID: 31342620 Abstract Title:  Genistein inhibits nasopharyngeal cancer stem cells through sonic hedgehog signaling. Abstract:  Genistein, a soy derived isoflavanoid compound, exerts anticancer effects in various cancers. Nasopharyngeal cancer stem cells (NCSCs) are a small subpopulation of cancer cells which are responsible for initiation, progression, …

Genistein exhibits significant anticancer activity against liver cancer.

PMID:  Arch Med Sci. 2019 Jul ;15(4):1001-1009. Epub 2018 Oct 3. PMID: 31360194 Abstract Title:  Genistein-triggered anticancer activity against liver cancer cell line HepG2 involves ROS generation, mitochondrial apoptosis, G2/M cell cycle arrest and inhibition of cell migration. Abstract:  Introduction: Liver cancer is one of the most common malignancies across the globe and one of …

Propolis mouthwash is effective and safe in the treatment of severe oral mucositis.

PMID:  Support Care Cancer. 2018 Dec ;26(12):4001-4009. Epub 2018 Jul 19. PMID: 30022350 Abstract Title:  Meta-analysis of randomized controlled trials of the efficacy of propolis mouthwash in cancer therapy-induced oral mucositis. Abstract:  PURPOSE: This meta-analysis aimed to evaluate the efficacy and safety of propolis mouthwash in cancer patients with therapy-induced oral mucositis.METHODS: This was a …

Bioactive components of propolis exhibit cytotoxic activity in human breast cancer cells.

PMID:  Cell Mol Biol (Noisy-le-grand). 2018 Jun 25 ;64(8):1-10. Epub 2018 Jun 25. PMID: 29981677 Abstract Title:  Flavonoids, bioactive components of propolis, exhibit cytotoxic activity and induce cell cycle arrest and apoptosis in human breast cancer cells MDA-MB-231 and MCF-7 – a comparative study. Abstract:  Breast cancer is one of the most common causes of …

Algerian propolis reverses multidrug resistance in resistant human lung adenocarcinoma cells.

PMID:  Anticancer Agents Med Chem. 2018 ;18(9):1330-1337. PMID: 30088453 Abstract Title:  Reversing Multidrug Resistance in Chemo-resistant Human Lung Adenocarcinoma (A549/DOX) Cells by Algerian Propolis Through Direct Inhibiting the P-gp Efflux-pump, G0/G1 Cell Cycle Arrest and Apoptosis Induction. Abstract:  BACKGROUND: Lung cancer is one of the most common malignancies with the highest incidence and mortality rate …

Chinese propolis exerts anti-proliferation effects in human melanoma cells.

PMID:  Nutrients. 2018 Aug 26 ;10(9). Epub 2018 Aug 26. PMID: 30149677 Abstract Title:  Chinese Propolis Exerts Anti-Proliferation Effects in Human Melanoma Cells by Targeting NLRP1 Inflammatory Pathway, Inducing Apoptosis, Cell Cycle Arrest, and Autophagy. Abstract:  Melanoma is a malignant tumor that begins in the melanocyte and has the highest mortality rate among all cutaneous …

Okinawa propolis components might be beneficial in the treatment of inflammation, type 2 diabetes mellitus, and Alzheimer’s disease.

PMID:  Molecules. 2018 Sep 27 ;23(10). Epub 2018 Sep 27. PMID: 30262742 Abstract Title:  Anti-Inflammatory, Anti-Diabetic, and Anti-Alzheimer's Effects of Prenylated Flavonoids from Okinawa Propolis: An Investigation by Experimental and Computational Studies. Abstract:  Okinawa propolis (OP) and its major ingredients were reported to have anti-cancer effects and lifespan-extending effects onthrough inactivation of the oncogenic kinase, …

The chemical composition and events related to the cytotoxic effects of propolis on osteosarcoma cells.

PMID:  Phytother Res. 2019 Mar ;33(3):591-601. Epub 2018 Nov 28. PMID: 30488503 Abstract Title:  The chemical composition and events related to the cytotoxic effects of propolis on osteosarcoma cells: A comparative assessment of Colombian samples. Abstract:  Osteosarcoma (OSA) is a type of bone cancer showing an aggressive biological behavior with metastatic progression. Because propolis potential …

Biochemical and morphological evaluation of the effects of propolis on cisplatin induced kidney damage in rats.

PMID:  Biotech Histochem. 2019 Apr ;94(3):204-213. Epub 2018 Dec 4. PMID: 30512970 Abstract Title:  Biochemical and morphological evaluation of the effects of propolis on cisplatin induced kidney damage in rats. Abstract:  Cisplatin (CP) is a chemotherapeutic agent used to treat various types of cancer; nephrotoxicity is the most common adverse effect of the drug. We …

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