PMID: Mol Med Rep. 2019 Aug ;20(2):1808-1818. Epub 2019 Jun 18. PMID: 31257529 Abstract Title: Benzyl isothiocyanate suppresses development and metastasis of murine mammary carcinoma by regulating the Wnt/β‑catenin pathway. Abstract: Benzyl isothiocyanate (BITC) has been reported to exhibit antitumor properties in various cancer types; however, the underlying mechanisms of its action remain unclear. In …
Author Archives: Taylor Mercado
Sulforaphane can inhibit growth of and induce cell cycle arrest in cancer cells.
PMID: J Med Food. 2019 May ;22(5):444-450. PMID: 31084542 Abstract Title: Sulforaphane Decrease of SERTAD1 Expression Triggers G1/S Arrest in Breast Cancer Cells. Abstract: Studies have identified the potential of chemopreventive effects of sulforaphane (SFN); however, the underlying mechanisms of its effect on breast cancer require further elucidation. This study investigated the anticancer effects of …
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Sulforaphane prevents PC12 cells from oxidative damage via the Nrf2 pathway.
PMID: Mol Med Rep. 2019 Jun ;19(6):4890-4896. Epub 2019 Apr 10. PMID: 31059012 Abstract Title: Sulforaphane prevents PC12 cells from oxidative damage via the Nrf2 pathway. Abstract: : The aim of this study was to investigate the protective effect of sulforaphane (SFN) on 1‑methyl‑4‑phenyl pyridine ion (MPP+)‑induced cytotoxicity and to investigate its possible mechanisms.METHODS: PC12 …
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Sulforaphane induces miR135b-5p and its target gene to inhibit the progression of pancreatic cancer.
PMID: Mol Ther Oncolytics. 2019 Sep 27 ;14:74-81. Epub 2019 Apr 6. PMID: 31044154 Abstract Title: Sulforaphane Induces miR135b-5p and Its Target Gene, RASAL2, thereby Inhibiting the Progression of Pancreatic Cancer. Abstract: Pancreatic ductal adenocarcinoma (PDA) is one of the most lethal tumors, with poor therapeutic options in the advanced state. The broccoli-derived anti-inflammatory agent …
The radioprotective effect of N-acetylcysteine against x-radiation-induced renal injury in rats.
PMID: Environ Sci Pollut Res Int. 2019 Aug 7. Epub 2019 Aug 7. PMID: 31392607 Abstract Title: The radioprotective effect of N-acetylcysteine against x-radiation-induced renal injury in rats. Abstract: The purpose of this study was therefore to investigate the effects of radiotherapy on the kidney and the potential use of agents such as N-acetylcysteine (NAC) …
Those living in the vicinity of a mobile phone base station (500 m) reported slightly more health complaints than others that cannot be fully explained by concerns about electromagnetic field exposure.
PMID: Occup Environ Med. 2009 Feb ;66(2):118-23. Epub 2008 Nov 18. PMID: 19017702 Abstract Title: Mobile phone base stations and adverse health effects: phase 1 of a population-based, cross-sectional study in Germany. Abstract: OBJECTIVE: The aim of this first phase of a cross-sectional study from Germany was to investigate whether proximity of residence to mobile …
Electromagnetic fields in neonatal incubators may interfere with melatonin and vagal tone in both neonates and caregivers.
PMID: J Matern Fetal Neonatal Med. 2019 Feb ;32(4):695-699. Epub 2017 Oct 23. PMID: 28988507 Abstract Title: Electromagnetic fields in neonatal incubators: the reasons for an alert. Abstract: BACKGROUND: Neonatal incubators are important tools for sick newborns in the first few days of life. Nevertheless, their electric engine, often very close to the newborn's body, …
This study emphasizes the need for a DNA-based biological electromagnetic field exposure threshold and outlines the changes to DNA that can occur even at extremely low levels of exposure.
PMID: Pathophysiology. 2009 Aug ;16(2-3):71-8. Epub 2009 Mar 5. PMID: 19268550 Abstract Title: Electromagnetic fields stress living cells. Abstract: Electromagnetic fields (EMF), in both ELF (extremely low frequency) and radio frequency (RF) ranges, activate the cellular stress response, a protective mechanism that induces the expression of stress response genes, e.g., HSP70, and increased levels of …
High long-term exposure to extremely low frequency and radiofrequency electromagnetic fields may lead to breast cancer and Alzheimer’s disease through amyloid-beta upregulation and melatonin downregulation.
PMID: Pathophysiology. 2009 Aug ;16(2-3):149-56. Epub 2009 Mar 10. PMID: 19278839 Abstract Title: Long-term exposure to magnetic fields and the risks of Alzheimer's disease and breast cancer: Further biological research. Abstract: OBJECTIVE: Extremely low frequency (ELF) and radio frequency (RF) magnetic fields (MFs) pervade our environment. Whether or not these magnetic fields are associated with …
Piceatannol protects against cisplatin induced nephrotoxicity.
PMID: Naunyn Schmiedebergs Arch Pharmacol. 2019 Jun 14. Epub 2019 Jun 14. PMID: 31197431 Abstract Title: Piceatannol protects against cisplatin nephrotoxicity via activation of Nrf2/HO-1 pathway and hindering NF-κB inflammatory cascade. Abstract: This study investigates the molecular mechanisms of the nephroprotective effect of piceatannol (PIC) against cisplatin-induced nephrotoxicity in rats. PIC (10 mg/kg i.p.) was given for …
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