N-acetylcysteine therapeutically protects against pulmonary fibrosis in a mouse model of silicosis.

PMID:  Biosci Rep. 2019 Jul 31 ;39(7). Epub 2019 Jul 18. PMID: 31273057 Abstract Title:  N-acetylcysteine tiherapeutically protects against pulmonary fibrosis in a mouse model of silicosis. Abstract:  Silicosis is a lethal pneumoconiosis disease characterized by chronic lung inflammation and fibrosis. The present study was to explore the effect of against crystalline silica (CS)-induced pulmonary …

N-acetylcysteine alleviated paraquat-induced mitochondrial fragmentation and autophagy in primary murine neural progenitor cells.

PMID:  J Appl Toxicol. 2019 Aug 1. Epub 2019 Aug 1. PMID: 31368586 Abstract Title:  N-acetylcysteine alleviated paraquat-induced mitochondrial fragmentation and autophagy in primary murine neural progenitor cells. Abstract:  The developing brain is uniquely vulnerable to toxic chemical exposures. Studies indicate that neural stem cell (NSC) self-renewal is susceptible to oxidative stress caused by xenobiotics. …

Cephalexin-associated achilles tendonitis: Case report and review of drug-induced tendinopathy.

PMID:  Cureus. 2018 Dec 27 ;10(12):e3783. Epub 2018 Dec 27. PMID: 30915263 Abstract Title:  Cephalexin-associated Achilles Tendonitis: Case Report and Review of Drug-induced Tendinopathy. Abstract:  Tendon disorders include tenosynovitis or tendonitis, tendinosis, and tendon rupture. Tendinopathy associated with drug administration has been associated with the systemic or local administration of several medications. A 90-year-old man …

Bisphenol A affects estradiol metabolism by targeting CYP1A1 and CYP19A1 in human placental JEG-3 cells.

PMID:  Toxicol In Vitro. 2019 Jul 30:104615. Epub 2019 Jul 30. PMID: 31374317 Abstract Title:  Bisphenol A affects estradiol metabolism by targeting CYP1A1 and CYP19A1 in human placental JEG-3 cells. Abstract:  Estradiol, in some way or another, plays a critically important physiologic role in the establishment and maintenance of pregnancy. This study was designed to …

N-acetylcysteine as an adjuvant therapy for Helicobacter pylori eradication.

PMID:  Cochrane Database Syst Rev. 2019 Feb 12 ;2:CD012357. Epub 2019 Feb 12. PMID: 30746681 Abstract Title:  N-acetylcysteine as an adjuvant therapy for Helicobacter pylori eradication. Abstract:  BACKGROUND: Helicobacter pylori (H pylori) is one of the most common pathogens to establish and cause infection in human beings, affecting about 50% of the world's population. Prevalence …

Protective effect of coenzyme Q10 against bisphenol-A-induced toxicity in the rat testes.

PMID:  Toxicol Ind Health. 2019 Jul ;35(7):466-481. PMID: 31364507 Abstract Title:  Protective effect of coenzyme Q10 against bisphenol-A-induced toxicity in the rat testes. Abstract:  The present study was conducted to investigate the antioxidant, histomorphometric, histochemical, immunohistochemical, biochemical, and cytological effects of coenzyme Q10 (CoQ10) against bisphenol-A (BPA)-induced testicular toxicity in rats. A total of 40 …

Neuro-toxic and reproductive effects of BPA.

PMID:  Curr Neuropharmacol. 2019 Jul 26. Epub 2019 Jul 26. PMID: 31362658 Abstract Title:  Neuro-toxic and reproductive effects of BPA. Abstract:  BACKGROUND: Bisphenol A (BPA) is one of the highest volume chemicals produced worldwide. It has recognized activity as an endocrine disrupting chemical and has suspected roles as a neurological and reproductive toxicant. It interferes …

Bisphenol A and bisphenol S exposures during pregnancy and gestational age.

PMID:  Chemosphere. 2019 Jul 22 ;237:124426. Epub 2019 Jul 22. PMID: 31362131 Abstract Title:  Bisphenol A and bisphenol S exposures during pregnancy and gestational age – A longitudinal study in China. Abstract:  Bisphenol A (BPA) and its substitute bisphenol S (BPS) are endocrine-disrupting chemicals and metabolized rapidly in human body. BPA exposure in late pregnancy …

Bisphenol A exposure under metabolic stress induces accelerated cellular senescence in vivo in a p53 independent manner.

PMID:  Sci Total Environ. 2019 Jun 25 ;689:1201-1211. Epub 2019 Jun 25. PMID: 31358486 Abstract Title:  Bisphenol A exposure under metabolic stress induces accelerated cellular senescence in vivo in a p53 independent manner. Abstract:  Senescence is an irreversible process that is a characteristic of age-associated disease like Type 2 diabetes (T2D). Bisphenol-A (BPA), one of …

Canned food intake and urinary bisphenol a concentrations.

PMID:  Environ Sci Pollut Res Int. 2019 Jul 27. Epub 2019 Jul 27. PMID: 31352597 Abstract Title:  Canned food intake and urinary bisphenol a concentrations: a randomized crossover intervention study. Abstract:  Bisphenol A (BPA) is an endocrine disruptor. To evaluate the effect of canned food consumption on internal BPA dose, urinary BPA concentrations were measured …

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