Taylor Mercado

Ursolic acid reverses the chemoresistance of breast cancer cells to paclitaxel.

PMID: Front Oncol. 2019 ;9:501. Epub 2019 Jun 14. PMID: 31259152 Abstract Title: Ursolic Acid Reverses the Chemoresistance of Breast Cancer Cells to Paclitaxel by Targeting MiRNA-149-5p/MyD88. Abstract: Paclitaxel (PTX) is widely used as a front-line chemotherapy for breast cancer treatment. However, its clinical applications are limited by the development of chemoresistance. The objective of …

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Ameliorative effect of ursolic acid on ochratoxin A-induced renal cytotoxicity.

PMID: Toxicon. 2019 Jul 26. Epub 2019 Jul 26. PMID: 31356822 Abstract Title: Ameliorative effect of ursolic acid on ochratoxin A-induced renal cytotoxicity mediated by Lonp1/Aco2/Hsp75. Abstract: Ochratoxin A (OTA) is a mycotoxin ubiquitous in feeds and foodstuffs. The water-insoluble pentacyclic triterpene bioactive compound, ursolic acid (UA), is widespread in various cuticular waxes of edible …

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Crataegus aronia has protective effects against high-fat diet-induced vascular inflammation.

PMID: Cardiovasc Toxicol. 2019 Jun 11. Epub 2019 Jun 11. PMID: 31183600 Abstract Title: The Protective Effect of Crataegus aronia Against High-Fat Diet-Induced Vascular Inflammation in Rats Entails Inhibition of the NLRP-3 Inflammasome Pathway. Abstract: This study investigated whether the whole-plant aqueous extract of Crataegus aronia (C. aronia) could protect against or alleviate high-fat diet …

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Antioxidant and anti-inflammatory mechanisms of neuroprotection by ursolic acid.

PMID: Oxid Med Cell Longev. 2019 ;2019:8512048. Epub 2019 May 16. PMID: 31223427 Abstract Title: Antioxidant and Anti-inflammatory Mechanisms of Neuroprotection by Ursolic Acid: Addressing Brain Injury, Cerebral Ischemia, Cognition Deficit, Anxiety, and Depression. Abstract: Ursolic acid (UA) is a pentacyclic triterpene which is found in common herbs and medicinal plants that are reputed for …

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The fruit of Crataegus pinnatifida ameliorates memory deficits in β-amyloid protein-induced Alzheimer’s disease model.

PMID: J Ethnopharmacol. 2019 Jul 23 ;243:112107. Epub 2019 Jul 23. PMID: 31349027 Abstract Title: The fruit of Crataegus pinnatifida ameliorates memory deficits inβ-amyloid protein-induced Alzheimer's disease mouse model. Abstract: ETHNOPHARMACOLOGICAL RELEVANCE: The fruit of Crataegus pinnatifida is a traditional medicine widely used as digestive drug in East Asia. Although Chinese herbal medicine used it …

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These findings suggest that hawthorn polyphenol extract can be used as the base ingredient for antiphotoaging food products.

PMID: J Food Biochem. 2019 Feb ;43(2):e12708. Epub 2018 Nov 11. PMID: 31353662 Abstract Title: Protective effects of hawthorn (Crataegus pinnatifida) polyphenol extract against UVB-induced skin damage by modulating the p53 mitochondrial pathway in vitro and in vivo. Abstract: This study investigated the effect of a hawthorn polyphenol extract (HPE) on ultraviolet B (UVB)-induced damage …

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A review of the effects of Chinese hawthorn on metabolic syndrome.

PMID: Iran J Basic Med Sci. 2019 May ;22(5):460-468. PMID: 31217924 Abstract Title: The effects of(Chinese hawthorn) on metabolic syndrome: A review. Abstract: Metabolic syndrome is described as a group of risk factors in which at least three unhealthy medical conditions, including obesity, high blood sugar, hypertension or dyslipidemia occur simultaneously in a patient. These …

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Anticancer effect of ursolic acid via mitochondria-dependent pathways.

PMID: Oncol Lett. 2019 Jun ;17(6):4761-4767. Epub 2019 Mar 19. PMID: 31186681 Abstract Title: Anticancer effect of ursolic acid via mitochondria-dependent pathways. Abstract: Ursolic acid is a plant-derived pentacyclic triterpenoid found in various medicinal herbs and fruits. It has generated clinical interest due to its anti-inflammatory, antioxidative, antiapoptotic and anticarcinogenic effects. An increasing amount of …

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Ursolic acid alleviates airway-vessel remodeling and muscle consumption in cigarette smoke-induced emphysema rats.

PMID: BMC Pulm Med. 2019 Jun 6 ;19(1):103. Epub 2019 Jun 6. PMID: 31170951 Abstract Title: Ursolic acid alleviates airway-vessel remodeling and muscle consumption in cigarette smoke-induced emphysema rats. Abstract: BACKGROUND: This study assessed the effects of ursolic acid (UA) on airway-vessel remodeling and muscle atrophy in cigarette smoke (CS)-induced emphysema rats and investigated potential …

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Pilates method was beneficial in the treatment of patients with Chikungunya fever.

PMID: Clin Rehabil. 2019 Jun 24:269215519856675. Epub 2019 Jun 24. PMID: 31230466 Abstract Title: Pilates method in the treatment of patients with Chikungunya fever: a randomized controlled trial. Abstract: OBJECTIVE: The aim of this study was to evaluate the effects of the Pilates method on the reduction of pain, improvement of joint function, and quality …

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