Wild blueberry anthocyanins inhibit inflammatory gene expression in vitro.

PMID:  J Agric Food Chem. 2014 Jul 23 ;62(29):7022-8. Epub 2014 Jan 17. PMID: 24397282 Abstract Title:  Inhibitory effects of wild blueberry anthocyanins and other flavonoids on biomarkers of acute and chronic inflammation in vitro. Abstract:  Wild lowbush blueberries (Vaccinium angustifolium Ait) are a rich source of anthocyanins and other flavonoids with anti-inflammatory activities; however, …

Anthocyanins from wild blueberry reduce the activation of NF-kB and mitigate IL-1B activity human intestinal cells.

PMID:  J Agric Food Chem. 2014 Aug 20 ;62(33):8346-51. Epub 2014 Aug 8. PMID: 25075866 Abstract Title:  Immunomodulatory effect of a wild blueberry anthocyanin-rich extract in human Caco-2 intestinal cells. Abstract:  Intestinal inflammation is a natural process crucial for the maintenance of gut functioning. However, abnormal or prolonged inflammatory responses may lead to the onset …

Wild blueberries alleviate inflammation and hypertension associated with developing obesity in mice fed with a high-fat diet.

PMID:  PLoS One. 2014 ;9(12):e114790. Epub 2014 Dec 12. PMID: 25501421 Abstract Title:  Wild blueberries (Vaccinium myrtillus) alleviate inflammation and hypertension associated with developing obesity in mice fed with a high-fat diet. Abstract:  BACKGROUND: Low-grade metabolic inflammation and hypertension are primary mechanisms involved in obesity-associated adverse health effects. Berries, especially Nordic wild blueberries (hereafter referred …

Anthocyanins and phenolic acids from a wild blueberry powder counteract lipid accumulation in THP-1-derived macrophages.

PMID:  Eur J Nutr. 2016 Feb ;55(1):171-82. Epub 2015 Jan 17. PMID: 25595100 Abstract Title:  Anthocyanins and phenolic acids from a wild blueberry (Vaccinium angustifolium) powder counteract lipid accumulation in THP-1-derived macrophages. Abstract:  PURPOSE: Blueberries are a rich source of anthocyanins (ACNs) and phenolic acids (PA), which are hypothesized to protect against development of atherosclerosis. …

Wild blueberry consumption attenuates local inflammation in the perivascular adipose tissue of obese Zucker rats.

PMID:  Appl Physiol Nutr Metab. 2016 Oct ;41(10):1045-1051. Epub 2016 Sep 26. PMID: 27669020 Abstract Title:  Wild blueberry consumption attenuates local inflammation in the perivascular adipose tissue of obese Zucker rats. Abstract:  Perivascular adipose tissue (PVAT) has been shown to play important roles in regulating vascular tone and linking local and systemic vascular inflammation. We …

Short-term consumption of wild blueberry juice may promote cardioprotective effects, by improving systolic blood pressure, possibly through nitric oxide production, in adults at risk for type 2 diabetes.

PMID:  BMC Nutr. 2017 ;3:45. Epub 2017 May 25. PMID: 32153825 Abstract Title:  The effects of 100% wild blueberry () juice consumption on cardiometablic biomarkers: a randomized, placebo-controlled, crossover trial in adults with increased risk for type 2 diabetes. Abstract:  Background: Wild blueberries have a high content of polyphenols, but there is limited data evaluating …

Additional health benefits accrue with greater increases in daily step counts.

PMID:  Curr Cardiovasc Risk Rep. 2010 Jul ;4(4):271-276. Epub 2010 Apr 30. PMID: 20672110 Abstract Title:  Steps to Better Cardiovascular Health: How Many Steps Does It Take to Achieve Good Health and How Confident Are We in This Number? Abstract:  Pedometers and other types of step-counting devices are growing in popularity with both researchers and …

This study determined that a 12,000 step per day guideline for children and youth between 6 and 19 years of age is a good estimate of meeting the current physical activity guideline.

PMID:  Med Sci Sports Exerc. 2012 May ;44(5):977-82. PMID: 22051570 Abstract Title:  Daily step target to measure adherence to physical activity guidelines in children. Abstract:  PURPOSE: There is a lack of robust evidence to support a daily step count target that equates to current physical activity guidelines in children and youth. This information would be …

More than 10,000 steps daily may be needed to maintain bone mineral density.

PMID:  Osteoporos Int. 2011 Dec ;22(12):2981-8. Epub 2011 Feb 12. PMID: 21318440 Abstract Title:  Maintaining femoral bone density in adults: how many steps per day are enough? Abstract:  UNLABELLED: The amount and intensity of walking to maintain a healthy skeleton is unknown. This study examined the relationship between habitual walking activity and femoral bone mineral …

Type 2 diabetic patients instructed to walk 10,000 steps per day increased HDL-C and resting energy expenditure and reduced plasminogen-activator inhibitor 1.

PMID:  Metabolism. 2006 Oct ;55(10):1382-7. PMID: 16979410 Abstract Title:  Efficacy of a pedometer-based physical activity program on parameters of diabetes control in type 2 diabetes mellitus. Abstract:  The aim of the study was to determine whether a recommendation to walk 10000 steps per day would result in significant improvements in glycemic control, insulin sensitivity, and …

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