PMID: Oxid Med Cell Longev. 2018 ;2018:5438179. Epub 2018 Jun 6. PMID: 29977456 Abstract Title: Anticancer Activity of Sulforaphane: The Epigenetic Mechanisms and the Nrf2 Signaling Pathway. Abstract: Sulforaphane (SFN), a compound derived from cruciferous vegetables that has been shown to be safe and nontoxic, with minimal/no side effects, has been extensively studied due to …
Author Archives: Taylor Mercado
Fermented dried Citrus unshiu peel extracts may be a therapeutic candidate for the treatment of inflammation and dry skin.
PMID: Pharm Biol. 2019 Dec ;57(1):392-402. PMID: 31188689 Abstract Title: Fermented driedpeel extracts exert anti-inflammatory activities in LPS-induced RAW264.7 macrophages and improve skin moisturizing efficacy in immortalized human HaCaT keratinocytes. Abstract: Markovich (Rutaceae) peel is known to contain high concentrations of flavonoids and exerts pharmacological effects on antioxidant, anti-inflammation, allergies, diabetes and viral infections.Very little …
Anti-inflammatory effect of Pomelo peel and its bioactive coumarins.
PMID: J Agric Food Chem. 2019 Jul 18. Epub 2019 Jul 18. PMID: 31318199 Abstract Title: Anti-inflammatory effect of Pomelo peel and its bioactive coumarins. Abstract: Citrus grandis (L.) Osbeck is a popular fruit cultivated around the world and its peels are sometimes used for the treatment of cough, abdominal pain and indigestion in China. …
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Effect of citrus peel extracts on the cellular quiescence of prostate cancer cells.
PMID: Food Funct. 2019 Jun 19 ;10(6):3727-3737. PMID: 31169845 Abstract Title: Effect of citrus peel extracts on the cellular quiescence of prostate cancer cells. Abstract: The re-entry of quiescent cancer cells to the cell cycle plays a key role in cancer recurrence, which can pose a high risk after primary treatment. Citrus peel extracts (CPEs) …
Hesperidin has a potential radioprotective agent against ionizing radiation-induced damage.
PMID: Medicina (Kaunas). 2019 Jul 12 ;55(7). Epub 2019 Jul 12. PMID: 31336963 Abstract Title: Radioprotective Effect of Hesperidin: A Systematic Review. Abstract: : Ionizing radiation (IR) has been of immense benefit to man, especially for medical purposes (diagnostic imaging and radiotherapy). However, the risks of toxicity in healthy normal cells, leading to cellular damage …
Sulforaphane protects against cadmium-induced testicular injury by activation of Nrf2-ARE pathway.
PMID: Molecules. 2018 Jul 19 ;23(7). Epub 2018 Jul 19. PMID: 30029485 Abstract Title: Protective Mechanism of Sulforaphane on Cadmium-Induced Sertoli Cell Injury in Mice Testis via Nrf2/ARE Signaling Pathway. Abstract: The present study evaluated the mechanism underlying the protective effect of sulforaphane (SFN) on cadmium (Cd)-induced Sertoli cell (TM4 cells) injury in mice. The …
Sulforaphane pre-treatment effectively protects bovine ovarian granulosa cells from oxidative stress damage through Nrf2-ARE activation.
PMID: Cell Tissue Res. 2018 Dec ;374(3):629-641. Epub 2018 Jul 21. PMID: 30032437 Abstract Title: Sulforaphane protects granulosa cells against oxidative stress via activation of NRF2-ARE pathway. Abstract: Sulforaphane (SFN) has been considered as an indirect antioxidant and potential inducer of the Nrf2-ARE pathway. This study was conducted to investigate the protective role of SFN …
Hesperidin ameliorates hyperglycemia by regulating key enzymes of carbohydrate metabolism.
PMID: Toxicol Mech Methods. 2019 Jul 25:1-32. Epub 2019 Jul 25. PMID: 31345080 Abstract Title: Hesperidin, a citrus flavonoid ameliorates hyperglycemia by regulating key enzymes of carbohydrate metabolism in streptozotocin induced diabetic rats. Abstract: The present study was investigated the protective effect of hesperidin on carbohydrate metabolizing enzymes in streptozotocin induced diabetic rats. Hesperidin was …
Sulforaphane combats colon cancer in vitro by inhibiting COX-2 and prostaglandin E1 synthase and exhibiting anti-angiogenic, anti-proliferative, and anti-metastatic properties.
PMID: Cells Tissues Organs. 2018 ;206(1-2):46-53. Epub 2018 Jul 24. PMID: 30041241 Abstract Title: Sulforaphane, a Chemopreventive Compound, Inhibits Cyclooxygenase-2 and Microsomal Prostaglandin E Synthase-1 Expression in Human HT-29 Colon Cancer Cells. Abstract: BACKGROUND: A high expression of prostaglandin E2 (PGE2) is found in colorectal cancer. Therefore, blocking of PGE2 generation has been identified as …
Quercetin mediated salt tolerance in tomato through the enhancement of plant antioxidant defense and glyoxalase systems.
PMID: Plants (Basel). 2019 Jul 25 ;8(8). Epub 2019 Jul 25. PMID: 31349715 Abstract Title: Quercetin Mediated Salt Tolerance in Tomato through the Enhancement of Plant Antioxidant Defense and Glyoxalase Systems. Abstract: Quercetin (Qu) is a strong antioxidant among the phenolic compounds having physiological and biochemical roles in plants. Hence, we have studied the Qu …
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