PMID: J Reprod Immunol. 2019 Feb ;131:44-49. Epub 2018 Dec 29. PMID: 30641297 Abstract Title: Pro- and anti-inflammatory effects of sulforaphane on placental cytokine production. Abstract: Placental inflammation increases the risk of adverse pregnancy outcomes and possibly neurodevelopmental disorders in the offspring. Previous research suggests it may be possible to modulate the placental immune response …
Author Archives: Taylor Mercado
Sulforaphane has the potential to prevent neuronal disorders by enhancing Brain-derived Neurotrophic Factor (BDNF) and its TrkB signaling pathways.
PMID: Mol Nutr Food Res. 2017 02 ;61(2). Epub 2016 Nov 30. PMID: 27735126 Abstract Title: Sulforaphane epigenetically enhances neuronal BDNF expression and TrkB signaling pathways. Abstract: SCOPE: Brain-derived neurotrophic factor (BDNF) is a neurotrophin that supports the survival of existing neurons and encourages the growth and differentiation of new neurons and synapses. We investigated …
Sulforaphane delays fibroblast aging in vitro by decreasing glycolysis and reducing oxidative stress.
PMID: Oxid Med Cell Longev. 2018 ;2018:5642148. Epub 2018 Nov 22. PMID: 30595796 Abstract Title: Sulforaphane Delays Fibroblast Senescence by Curbing Cellular Glucose Uptake, Increased Glycolysis, and Oxidative Damage. Abstract: Increased cell senescence contributes to the pathogenesis of aging and aging-related disease. Senescence of human fibroblastsmay be delayed by culture in low glucose concentration. There …
Anticancer effects of five biflavonoids from Ginkgo biloba flowers In vitro.
PMID: Molecules. 2019 Apr 16 ;24(8). Epub 2019 Apr 16. PMID: 30995808 Abstract Title: Anticancer Effects of Five Biflavonoids fromL. Male Flowers In Vitro. Abstract: L., an ancient dioecious gymnosperm, is now cultivated worldwide for landscaping and medical purposes. A novel biflavonoid-amentoflavone 7''-O-β-D-glucopyranoside ()-and four known biflavonoids were isolated and identified from the male flowers …
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Validation of a 16th century traditional Chinese medicine use of Ginkgo biloba as a topical antimicrobial.
PMID: Front Microbiol. 2019 ;10:775. Epub 2019 Apr 16. PMID: 31057504 Abstract Title: Validation of a 16th Century Traditional Chinese Medicine Use ofas a Topical Antimicrobial. Abstract: In the search for new therapeutic solutions to address an increasing number of multidrug-resistant bacterial pathogens, secondary metabolites from plants have proven to be a rich source of …
Ginkgo biloba leaf extract attenuates atherosclerosis in streptozotocin-induced diabetic mice.
PMID: Oxid Med Cell Longev. 2019 ;2019:8134678. Epub 2019 Mar 18. PMID: 31080547 Abstract Title: Ginkgo Biloba Leaf Extract Attenuates Atherosclerosis in Streptozotocin-Induced Diabetic ApoE-/- Mice by Inhibiting Endoplasmic Reticulum Stress via Restoration of Autophagy through the mTOR Signaling Pathway. Abstract: Background: There is a crosstalk between endoplasmic reticulum stress (ERS) and autophagy, and autophagy …
Roundup confers cytotoxicity through DNA damage and Mitochondria-Associated apoptosis induction.
PMID: Environ Pollut. 2019 May 29 ;252(Pt A):917-923. Epub 2019 May 29. PMID: 31226516 Abstract Title: Roundupconfers cytotoxicity through DNA damage and Mitochondria-Associated apoptosis induction. Abstract: Glyphosate-based herbicides (GBH) are the most widely used pesticides in the world. The extensive use of them increases the potential human health risk, including the human inhalation toxicity risk. …
Maternal glyphosate-based herbicide exposure alters antioxidant-related genes in the brain and serum metabolites of male rat offspring.
PMID: Neurotoxicology. 2019 Jun 18 ;74:121-131. Epub 2019 Jun 18. PMID: 31226268 Abstract Title: Maternal glyphosate-based herbicide exposure alters antioxidant-related genes in the brain and serum metabolites of male rat offspring. Abstract: In response to the rapid development of genetically engineered glyphosate-tolerant crops, the use of glyphosate-based herbicides (GBHs), in agriculture, has increased substantially. Currently, …
Glyphosate-based herbicide exposure during pregnancy and lactation malprograms the male reproductive morphofunction in F1 offspring.
PMID: J Dev Orig Health Dis. 2019 Jul 16:1-8. Epub 2019 Jul 16. PMID: 31309914 Abstract Title: Glyphosate-based herbicide exposure during pregnancy and lactation malprograms the male reproductive morphofunction in F1 offspring. Abstract: One of the most consumed pesticides in the world is glyphosate, the active ingredient in the herbicide ROUNDUP®. Studies demonstrate that glyphosate …
Developmental programming: Sex-specific programming of growth upon prenatal bisphenol A exposure.
PMID: J Appl Toxicol. 2019 Jul 23. Epub 2019 Jul 23. PMID: 31338854 Abstract Title: Developmental programming: Sex-specific programming of growth upon prenatal bisphenol A exposure. Abstract: In both human and animals, in utero exposure to bisphenol A (BPA), an endocrine-disrupting chemical used in the production of plastics and epoxy resins, has been shown to …
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