PMID: J Perinat Med. 2019 Jul 24. Epub 2019 Jul 24. PMID: 31339859 Abstract Title: Effect of bisphenol-A (BPA) on placental biomarkers for inflammation, neurodevelopment and oxidative stress. Abstract: Background Bisphenol-A (BPA) is a widespread pollutant whose effects on pregnant women are poorly understood. Therefore, we investigated the effects of BPA on basal and bacteria-stimulated …
Author Archives: Taylor Mercado
Selenium protection against mercury neurotoxicity: Modulation of apoptosis and autophagy in the anterior pituitary.
PMID: Life Sci. 2019 Jun 15:116578. Epub 2019 Jun 15. PMID: 31211996 Abstract Title: Selenium protection against mercury neurotoxicity: Modulation of apoptosis and autophagy in the anterior pituitary. Abstract: AIMS: The aim of the present study is to shed light on the modulating action of selenium on two of the most crucial cellular pathways; apoptosis …
Selenium-rich-yeast exerts a cardio-protective effect against aluminum-induced toxicity.
PMID: Biol Trace Elem Res. 2019 Jun 22. Epub 2019 Jun 22. PMID: 31230209 Abstract Title: Selenium-Rich-Yeast Protects Against Aluminum-Induced Activating Nuclear Xenobiotic Receptors and Triggering Inflammation and Cytochromes P450 Systems in Mice Heart. Abstract: Aluminum (Al) poisoning is linked to the development of cardiovascular diseases, and dietary supplementation with selenium-rich-yeast (SeY) has been shown …
Myricetin nanoliposomes induced SIRT3-mediated glycolytic metabolism leading to glioblastoma cell death
PMID: Artif Cells Nanomed Biotechnol. 2018 ;46(sup3):S180-S191. Epub 2019 Jan 28. PMID: 30691320 Abstract Title: Myricetin nanoliposomes induced SIRT3-mediated glycolytic metabolism leading to glioblastoma cell death. Abstract: As the most aggressive and malignant glioma, glioblastoma multiforme (GBM) abnormally expresses genes that mediate glycolytic metabolism and tumour cell growth. In this study, we investigated myricetin incorporated …
Myricetin attenuated hepatic steatosis via the miR-146b/TRb pathway and should be considered for the management of NAFLD conditions.
PMID: Food Funct. 2019 Mar 20 ;10(3):1465-1477. PMID: 30776032 Abstract Title: Myricetin alleviated hepatic steatosis by acting on microRNA-146b/thyroid hormone receptor b pathway in high-fat diet fed C57BL/6J mice. Abstract: Hepatic microRNAs (miRs) regulate local thyroid hormone (TH) action and TH-related lipid metabolism. We previously found that myricetin effectively ameliorated hepatic steatosis by targeting PPAR …
Myricetin ameliorates cytokine-induced migration and invasion of cholangiocarcinoma cells.
PMID: J Cancer Res Ther. 2019 Jan-Mar;15(1):157-163. PMID: 30880773 Abstract Title: Myricetin ameliorates cytokine-induced migration and invasion of cholangiocarcinoma cells via suppression of STAT3 pathway. Abstract: Aim of Study: Cholangiocarcinoma (CCA) is an aggressive cancer with considerable metastatic potential. Various cytokines secreted by tumor cells or cells in the tumor environment can promote the metastasis …
Myricetin attenuates the severity of seizures and neuroapoptosis.
PMID: Exp Ther Med. 2019 Apr ;17(4):3083-3091. Epub 2019 Feb 15. PMID: 30906480 Abstract Title: Myricetin attenuates the severity of seizures and neuroapoptosis in pentylenetetrazole kindled mice by regulating the of BDNF-TrkB signaling pathway and modulating matrix metalloproteinase-9 and GABA. Abstract: Currently available antiepileptic drugs are effective; however, frequently associated with adverse effects that limit …
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These results enrich the comprehensive bioactivities of myricetin and reveal that it has powerful anti-inflammatory properties.
PMID: Biomed Res Int. 2019 ;2019:3746326. Epub 2019 Mar 7. PMID: 30956980 Abstract Title: Microarray Based Functional Analysis of Myricetin and Proteomic Study on Its Anti-Inflammatory Property. Abstract: Myricetin has been reported as a promising chemopreventive compound with multiple biofunctions. To evaluate its influence on gene expressions in genome-wide set and further investigate its anti-inflammatory …
Myricetin suppresses the propagation of hepatocellular carcinoma.
PMID: Cells. 2019 04 17 ;8(4). Epub 2019 Apr 17. PMID: 30999669 Abstract Title: Myricetin Suppresses the Propagation of Hepatocellular Carcinoma via Down-Regulating Expression of YAP. Abstract: Myricetin is a naturally occurring flavonoid with protective effects against a variety of cancers. However, the molecular mechanism of myricetin against hepatocellular carcinoma (HCC) has still not been …
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Protective functions of myricetin in LPS-induced cardiomyocytes H9c2 cells.
PMID: Eur J Med Res. 2019 Apr 26 ;24(1):20. Epub 2019 Apr 26. PMID: 31027517 Abstract Title: Protective functions of myricetin in LPS-induced cardiomyocytes H9c2 cells injury by regulation of MALAT1. Abstract: BACKGROUND: Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is a crucial mediator in response to inflammation. Myricetin protects cardiomyocytes against inflammatory injury. However, it's …
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