PMID: Scand J Clin Lab Invest. 2011 Jul ;71(4):330-9. Epub 2011 Mar 17. PMID: 21413848 Abstract Title: Insulin induces fatty acid desaturase expression in human monocytes. Abstract: Increasing evidence suggests that fatty acid desaturases, rate-limiting enzymes in unsaturated fatty acid biosynthesis, are important factors in the pathogenesis of lipid-induced insulin resistance. The conversion of dihomogamma …
Author Archives: Taylor Mercado
This review suggests a predominant omega-3 concentration may prevent overreactive arachidonic acid cascades that contribute to pathophysiological inflammatory responses.
PMID: Biomed Res Int. 2015 ;2015:285135. Epub 2015 Aug 2. PMID: 26301244 Abstract Title: Omega-3 PUFAs Lower the Propensity for Arachidonic Acid Cascade Overreactions. Abstract: A productive view of the benefits from omega-3 (n-3) nutrients is that the dietary essential omega-6 (n-6) linoleic acid has a very narrow therapeutic window which is widened by n-3 …
Sesame lignans inhibit delta-5 desaturase activity, increasing dihomo-gamma-linoleic acid levels and decreasing prostaglandin E2 synthesis.
PMID: Prostaglandins Leukot Essent Fatty Acids. 1998 Mar ;58(3):185-91. PMID: 9610840 Abstract Title: Dietary alpha-linolenic acid increases TNF-alpha, and decreases IL-6, IL-10 in response to LPS: effects of sesamin on the delta-5 desaturation of omega6 and omega3 fatty acids in mice. Abstract: Sesamin (a non-fat portion of sesame seed oil) inhibits delta-5 desaturase activity resulting …
A high dihomo-gamma-linoleic acid/arachidonic acid ratio and high DGLA levels, but not AA levels, are associated with a better prognosis in patients with acute cardiovascular disease.
PMID: Lipids Health Dis. 2017 Aug 14 ;16(1):150. Epub 2017 Aug 14. PMID: 28806965 Abstract Title: Decreased circulating dihomo-gamma-linolenic acid levels are associated with total mortality in patients with acute cardiovascular disease and acute decompensated heart failure. Abstract: BACKGROUND: Polyunsaturated fatty acids (PUFAs) have important roles in the pathogenesis of cardiovascular diseases. However, the clinical …
Selenium-rich yeast mitigates aluminum-mediated testicular toxicity.
PMID: Biol Trace Elem Res. 2019 Jul 21. Epub 2019 Jul 21. PMID: 31327124 Abstract Title: Selenium-Rich Yeast Mitigates Aluminum-Mediated Testicular Toxicity by Blocking Oxidative Stress, Inhibiting NO Production, and Disturbing Ionic Homeostasis. Abstract: Aluminum (Al) poisoning has been linked to the development of several reproductive system dysfunctions. Dietary supplementation with selenium-rich yeast (SeY) has …
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Ginkgo biloba extract protects human melanocytes from H2O2-induced oxidative stress by activating Nrf2.
PMID: J Cell Mol Med. 2019 Aug ;23(8):5193-5199. Epub 2019 May 31. PMID: 31148371 Abstract Title: Ginkgo biloba extract protects human melanocytes from HO-induced oxidative stress by activating Nrf2. Abstract: Vitiligo is a common skin depigmenting disorder characterized by the loss of functional melanocytes. Its pathogenesis is complicated and oxidative stress plays a critical role …
G. biloba extracts might be a good option to improve certain neurodegenerative retinal diseases.
PMID: Planta Med. 2019 Jul 2. Epub 2019 Jul 2. PMID: 31266069 Abstract Title: Neuroprotective Potential of Ginkgo biloba in Retinal Diseases. Abstract: Like other tissues of the central nervous system, the retina is susceptible to damage by oxidative processes that result in several neurodegenerative disease such as age-related macular degeneration, diabetic retinopathy, glaucoma, ischaemic …
Ginkgo biloba pretreatment attenuates myocardial ischemia-reperfusion injury.
PMID: Am J Chin Med. 2019 Jul 21:1-17. Epub 2019 Jul 21. PMID: 31327236 Abstract Title: Pretreatment Attenuates Myocardial Ischemia-Reperfusion Injury via mitoBK. Abstract: extracts (EGb) alleviate myocardial ischemia/reperfusion (MI/R) injury. However, the underlying mechanisms have not yet been characterized. This study aimed to investigate whether activation of large-conductance Ca-activated Kchannels at the inner mitochondrial …
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Ginkgo biloba attenuates aluminum lactate-induced neurotoxicity in reproductive senescent female rats.
PMID: Environ Sci Pollut Res Int. 2019 Jul 18. Epub 2019 Jul 18. PMID: 31321719 Abstract Title: Ginkgo biloba attenuates aluminum lactate-induced neurotoxicity in reproductive senescent female rats: behavioral, biochemical, and histopathological study. Abstract: Extensive use of aluminum (Al) in industry, cooking utensils, and wrapping or freezing the food items, due to its cheapness and …
The restoration of the gut microbiome in patients with Parkinson’s disease and may alter its clinical progression.
PMID: J Neurogastroenterol Motil. 2019 Jul 1 ;25(3):363-376. PMID: 31327219 Abstract Title: Parkinson's Disease: The Emerging Role of Gut Dysbiosis, Antibiotics, Probiotics, and Fecal Microbiota Transplantation. Abstract: The role of the microbiome in health and human disease has emerged at the forefront of medicine in the 21st century. Over the last 2 decades evidence has …
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